Affect Clinical Trials

1 recruitingLast updated: May 4, 2026

Affect Trials at a Glance

110 actively recruiting trials for affect are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 57 trials, with the heaviest enrollment activity in Boston, Pittsburgh, and Belmont. Lead sponsors running affect studies include VA Office of Research and Development, Mclean Hospital, and Centre for Addiction and Mental Health.

Browse affect trials by phase

Treatments under study

About Affect Clinical Trials

Looking for clinical trials for Affect? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Affect trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Affect clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 110 trials

Recruiting
Not Applicable

Neural Mechanisms of Interpersonal Expectations on Negative Affect

Negative AffectivityNon-invasive Brain Stimulation
Trustees of Dartmouth College190 enrolled1 locationNCT06980090
Recruiting

Database Registry for Neural Network Biomarkers in Psychosis

SchizophreniaSchizoaffective Disorder
University of Texas Southwestern Medical Center1,000 enrolled1 locationNCT01409109
Recruiting
Not Applicable

ETASCAN Project: ETAS Project 2

MRISleepCognition+3 more
University of Reading60 enrolled1 locationNCT07550140
Recruiting

Cognitive Function and Affective Regulation in Meditators

Cognitive Function and Affective Regulation
Balachundhar Subramaniam104 enrolled1 locationNCT07546786
Recruiting
Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled19 locationsNCT07105111
Recruiting
Not Applicable

Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis

SchizophreniaPsychotic DisordersSchizo Affective Disorder
The Royal Ottawa Mental Health Centre52 enrolled1 locationNCT05973110
Recruiting
Not Applicable

Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous

Induction of Labor Affected Fetus / Newborn
Holy Family Hospital, Nazareth, Israel142 enrolled2 locationsNCT06325007
Recruiting
Not Applicable

Accelerated Transcranial Magnetic Stimulation for People With Schizophrenia Treated With Clozapine

SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.30 enrolled1 locationNCT06003036
Recruiting
Phase 1Phase 2

Acetazolamide for Treatment Resistant Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD60 enrolled2 locationsNCT04887792
Recruiting
Phase 2

Synbiotic Compound to Reduce Symptoms of Schizophrenia

SchizophreniaSchizoaffective Disorder
Sheppard Pratt Health System68 enrolled1 locationNCT04226898
Recruiting
Phase 1Phase 2

Ocrelizumab for Psychosis by Autoimmunity

SchizophreniaSchizo-Affective Type of Psychosis
The Methodist Hospital Research Institute40 enrolled1 locationNCT03971487
Recruiting

An Observational Study of Individuals With Isolated Dystonia

Isolated/Primary Dystonia That Affects More Than One Region of the Body
Vima Therapeutics200 enrolled29 locationsNCT07111663
Recruiting
Phase 1Phase 2

A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants

Active Noninfectious Uveitis Affecting the Posterior Segment
Regeneron Pharmaceuticals72 enrolled4 locationsNCT07218770
Recruiting
Phase 4

The Stimulation To Induce Mothers Study

Labor PainOxytocinPhysiologic Effects of Drugs+1 more
Yale University988 enrolled3 locationsNCT05079841
Recruiting

Brain Imaging of Cognition Inn Schizophrenia and Depression

Schizophrenia / Schizoaffective Disorder
The Royal Ottawa Mental Health Centre90 enrolled1 locationNCT04159662
Recruiting
Phase 1Phase 2

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Not Applicable

Cerebellar Modulation of Cognition in Psychosis

SchizophreniaPsychosisSchizoaffective Disorder+1 more
Mclean Hospital95 enrolled2 locationsNCT06107764
Recruiting
Not Applicable

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

Schizo Affective DisorderSCHIZOPHRENIA 1 (Disorder)
Nathan Kline Institute for Psychiatric Research120 enrolled1 locationNCT07469384
Recruiting

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

Idiopathic Pulmonary Arterial HypertensionHeritable Pulmonary Arterial HypertensionUnaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo+1 more
Vanderbilt University Medical Center150 enrolled1 locationNCT05584722
Recruiting
Not Applicable

Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study

SchizophreniaControl SubjectsSchizoaffective Disorder
Rutgers, The State University of New Jersey74 enrolled1 locationNCT06745479