Phase 1 Aging Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1Phase 2
Effect of a Daily Supplement on Plasma PAI-1 Levels
Endothelial DysfunctionAging
University of California, Los Angeles35 enrolled2 locationsNCT07469475
Recruiting
Phase 1
Rapalog Pharmacology (RAP PAC) Study
Aging
University of Wisconsin, Madison72 enrolled1 locationNCT05949658
Recruiting
Phase 1Phase 2
MTOR Inhibitors in Older Adults
Aging
University of Texas Southwestern Medical Center60 enrolled1 locationNCT06727305
Recruiting
Phase 1
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
Aging
University of California, Berkeley40 enrolled1 locationNCT06367738
Recruiting
Phase 1Phase 2
Establishing Best Treatment Strategy for T4 Esophageal Cancer
Esophageal Cancer TNM Staging Primary Tumor (T) T4
National Cheng-Kung University Hospital22 enrolled1 locationNCT06531434
Recruiting
Phase 1Phase 2
Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant
Hepatocellular Carcinoma (HCC)Liver Transplant SurgeryMacrovascular Invasion+1 more
University Health Network, Toronto48 enrolled2 locationsNCT06725121
Recruiting
Phase 1Phase 2
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
Walking, DifficultyAging WellHyperemia
University of North Texas Health Science Center72 enrolled1 locationNCT05706181
Completed
Phase 1
Staff as Change Agents – Sustaining Mental Health in Aged Care
Staff knowledge and skills to manage mental health protocols associated with depression and challenging behaviours associated with dementiaStaff factors such as stress, job satisfaction and staff turnoverPreventative and screening interventions of depression+2 more
Professor Marita McCabe468 enrolled1 locationACTRN12613000420741
Completed
Phase 1
A Phase I study to assess the safety of three formulations of the dermal implant ELAPR
The dermal implant ELAPR is being developed to treat the symptoms of skin aging or damage including wrinkles, scarring and photoaging.Healthy subjects are to be used in the study to assess the safety of the dermal implant.
Elastagen Pty Ltd12 enrolled1 locationACTRN12610000871044