Phase 2 Aging Clinical Trials

37 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 37 trials

Recruiting
Phase 2

Ketamine Alcohol (in Treatment-Resistant Depression)

Magnetic Resonance ImagingAlcoholismMajor Depression
Mark Niciu60 enrolled1 locationNCT02122562
Recruiting
Phase 2

Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder

Magnetic Resonance ImagingEcological Momentary AssessmentAttentional Bias+4 more
University of Arkansas255 enrolled1 locationNCT05336188
Recruiting
Phase 2

A Pilot Study to Correlate 4-18F- Fluoro-1-naphthol 18F-4FN PET/CT Imaging With Chronic Graft Versus Host Disease Manifestations

PET/CT ImagingPilot StudyHost Disease Manifestation
M.D. Anderson Cancer Center16 enrolled1 locationNCT07325253
Recruiting
Phase 2

Fisetin to Reduce Senescence and Mobility Impairment in PAD

ClaudicationPeripheral Arterial DiseaseAging+2 more
Northwestern University34 enrolled1 locationNCT06399809
Recruiting
Phase 2

Tirzepatide to Slow Biological Aging

AgingLONGEVITY 1
The University of Texas Medical Branch, Galveston90 enrolled1 locationNCT07220473
Recruiting
Phase 2Phase 3

Effect of Nutritional Ketosis on Alcohol Metabolism

Magnetic Resonance ImagingAlcohol DrinkingKetogenic Dieting+2 more
University of Pennsylvania20 enrolled1 locationNCT06065657
Recruiting
Phase 1Phase 2

Effect of a Daily Supplement on Plasma PAI-1 Levels

Endothelial DysfunctionAging
University of California, Los Angeles35 enrolled2 locationsNCT07469475
Recruiting
Phase 2

Brain Blood Vessel Responses to Changes in Blood Flow

Magnetic Resonance ImagingCerebrovascular Circulation
University of Wisconsin, Madison36 enrolled1 locationNCT06629077
Recruiting
Phase 2

Improving Physical Ability and Cellular Senescence Elimination in HIV

FrailtyHIVAging Problems+1 more
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled27 locationsNCT07144293
Recruiting
Phase 2

Exercise to Improve Brain Health in Older African Americans

Cognitive ChangeAlzheimer DiseaseAging+1 more
Rutgers, The State University of New Jersey280 enrolled1 locationNCT05597124
Recruiting
Phase 2

Fiber and Calcium Absorption in Older Men

Aging
VA Office of Research and Development30 enrolled1 locationNCT06519877
Recruiting
Phase 2Phase 3

Empagliflozin Reversal of Arterial StiffnEss in Aging

Arterial StiffnessAging
University of Missouri-Columbia80 enrolled1 locationNCT06506422
Recruiting
Phase 2

The Role of Sirolimus in Preventing Functional Decline in Older Adults

Aging
Irina Timofte10 enrolled1 locationNCT05237687
Recruiting
Phase 1Phase 2

MTOR Inhibitors in Older Adults

Aging
University of Texas Southwestern Medical Center60 enrolled1 locationNCT06727305
Recruiting
Phase 2

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

Cognitive DysfunctionAlzheimer DiseaseFatty Acids, Omega-3+3 more
Michal Schnaider Beeri, Ph.D.20 enrolled1 locationNCT07392723
Recruiting
Phase 2

The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults

FrailtyAgingMild Cognitive Impairment
UConn Health60 enrolled1 locationNCT06027554
Recruiting
Phase 2

Using Xe MRI to Guide Radiation Therapy for Lung Cancer

Imaging Techniques
Sean Fain15 enrolled1 locationNCT06925295
Recruiting
Phase 2

Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

Magnetic Resonance ImagingCerebrovascular Circulation
University of Wisconsin, Madison36 enrolled1 locationNCT06629090
Recruiting
Phase 2

Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study

Older AdultsCognitive DeclineAging+1 more
Washington University School of Medicine20 enrolled1 locationNCT07000734
Recruiting
Phase 2

Study of Healthy Aging and Physical Function With Elamipretide

Aging, Healthy
David Marcinek30 enrolled1 locationNCT07275424