Early Phase 1 Aging Clinical Trials

16 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 116 of 16 trials

Recruiting
Early Phase 1

Secretome Treatment for Facial Rejuvenation

Stem CellFacial AgingRejuvenation+1 more
Acorn Biolabs Inc.24 enrolled1 locationNCT07227883
Recruiting
Early Phase 1

iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009

Huntington’s DiseaseHuntington DiseasePositron Emission Tomography+6 more
CHDI Foundation, Inc.27 enrolled1 locationNCT06634628
Recruiting
Early Phase 1

Identification of Critical Thermal Environments for Aged Adults

Aging
Penn State University190 enrolled1 locationNCT04284397
Recruiting
Early Phase 1

Effect of Gut Microbiome Intervention on Aging Via Oral FMT

FrailtyAging
Chinese Academy of Medical Sciences, Fuwai Hospital210 enrolled6 locationsNCT05598112
Recruiting
Early Phase 1

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Endometrial CancerNear Infrared Fluorescence ImagingCYTALUX (Pafolacianine) Injection+1 more
Abramson Cancer Center at Penn Medicine10 enrolled2 locationsNCT07278986
Recruiting
Early Phase 1

Early Neurovascular Adaptations in Aging Women

WomenAgingBlood Flow+1 more
University of Missouri-Columbia64 enrolled1 locationNCT06520982
Recruiting
Early Phase 1

Heat, Microvascular Function and Aging

Aging
William Hughes20 enrolled1 locationNCT06633198
Recruiting
Early Phase 1

Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction

Type 2 DiabetesHealthy Aging
Medical College of Wisconsin60 enrolled1 locationNCT05593549
Recruiting
Early Phase 1

Angiotensin-(1-7) Cardiovascular Effects in Aging

Aging
Milton S. Hershey Medical Center26 enrolled1 locationNCT05301192
Recruiting
Early Phase 1

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

MenopauseHypoxiaAging+1 more
University of Missouri-Columbia75 enrolled1 locationNCT06417177
Recruiting
Early Phase 1

RESTOR: PK/PD mTORi Inhibition in Older Adults

Aging
The University of Texas Health Science Center at San Antonio194 enrolled1 locationNCT06658093
Recruiting
Early Phase 1

Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems

Aging
Weinberg Medical Physics LLC30 enrolled1 locationNCT06779188
Recruiting
Early Phase 1

Gene Expression Changes In Young and Geriatric Skin

AgingUVB Phototherapy BurnInsulin-like Growth Factor 1
Wright State University24 enrolled1 locationNCT03932162
Recruiting
Early Phase 1

Transient Receptor Potential Channels

Aging
Penn State University45 enrolled1 locationNCT06444594
Recruiting
Early Phase 1

68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients

Breast CancerProstate CancerBrain Tumor+1 more
Peking Union Medical College Hospital90 enrolled1 locationNCT05549024
Recruiting
Early Phase 1

Effects of Nicotine and Attention on Frequency Tuning in Auditory Cortex

Aging
University of California, Berkeley48 enrolled1 locationNCT05018117