Phase 2 AIN Clinical Trials
436 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 436 trials
Recruiting
Phase 1Phase 2
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Brain CancerGBMGlioma+12 more
National Institute of Neurological Disorders and Stroke (NINDS)40 enrolled1 locationNCT07416188
Recruiting
Phase 2
Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study
Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Phase 2
Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities
HPV InfectionASC-USUterine Cervical Dysplasia+3 more
Amplexd Therapeutics, Inc.45 enrolled1 locationNCT07572396
Recruiting
Phase 2
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled5 locationsNCT07326566
Recruiting
Phase 1Phase 2
Assessment of the Efficacy and Safety of Injectable TQB2934 (Subcutaneous Injection) in Systemic Light Chain Amyloidosis Patients
Systemic Light Chain Amyloidosis
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.70 enrolled27 locationsNCT07266116
Recruiting
Phase 2
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8+1 more
Roswell Park Cancer Institute23 enrolled3 locationsNCT04348747
Recruiting
Phase 2
Testing the Pain Clinical Practice Guideline
PainDementia
University of Maryland, Baltimore300 enrolled11 locationsNCT05858996
Recruiting
Phase 2
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 1Phase 2
Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
Tumors Metastatic to Brain
Case Comprehensive Cancer Center36 enrolled2 locationsNCT01891318
Recruiting
Phase 2
A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas
Brain TumorGlioblastoma
Case Comprehensive Cancer Center48 enrolled1 locationNCT07003542
Recruiting
Phase 2
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
Immune DysregulationPrimary Immune Regulatory DisorderChronic Granulomatous Disease+12 more
Paul Szabolcs25 enrolled1 locationNCT07284641
Recruiting
Phase 2
Modulating Exercise Dosage to Improve Concussion Recovery
TreatmentDepression, AnxietyAerobic Exercise+2 more
University of Colorado, Denver216 enrolled3 locationsNCT05434130
Recruiting
Phase 1Phase 2
A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma
Malignant Neoplasm of Brain
Novelwise Pharmaceutical Corporation15 enrolled3 locationsNCT07569042
Recruiting
Phase 2
Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy
Painful Diabetic Neuropathy
Dartmouth-Hitchcock Medical Center35 enrolled1 locationNCT04678895
Recruiting
Phase 1Phase 2
A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
CancerBrain Tumor
National Cancer Institute (NCI)96 enrolled1 locationNCT05588141
Recruiting
Phase 2
Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.
Breast Cancer Brain Metastases
Shanghai Pharmaceuticals Holding Co., Ltd52 enrolled25 locationsNCT05872347
Recruiting
Phase 2
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
Brain TumorGlioblastomaBrain Tumor, Recurrent+1 more
University of Birmingham120 enrolled22 locationsNCT05629702
Recruiting
Phase 2
A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
Chronic MigraineEpisodic Migraine
Ipsen641 enrolled166 locationsNCT06625060
Recruiting
Phase 1Phase 2
Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study
Diabetic NeuropathiesDiabetic Peripheral Neuropathic Pain (DPN)
Florida A&M University20 enrolled1 locationNCT07298408
Recruiting
Phase 2Phase 3
A Study of Buntanetap in Participants With PD
Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784