Phase 2 AIN Clinical Trials
464 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 464 trials
Recruiting
Phase 2
Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study
Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Phase 2
Screening Trial for Pain Relief in Schwannomatosis (STARFISH)
Pain, ChronicSchwannomatosisSchwannomas
Massachusetts General Hospital40 enrolled1 locationNCT05684692
Recruiting
Phase 2
Testing the Pain Clinical Practice Guideline
PainDementia
University of Maryland, Baltimore300 enrolled11 locationsNCT05858996
Recruiting
Phase 2
BCMA/CD3 Bispecific Antibody Treatment for Newly Diagnosed Amyloidosis
Systemic Light Chain Amyloidosis
Institute of Hematology & Blood Diseases Hospital, China21 enrolled1 locationNCT07151690
Recruiting
Phase 2
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled22 locationsNCT07326566
Recruiting
Phase 2
Impact of RADA16 Use on Outcomes Following Tonsillectomy in Children
Postoperative Pain
Rutgers, The State University of New Jersey134 enrolled2 locationsNCT07188779
Recruiting
Phase 2Phase 3
A Study of Buntanetap in Participants With PD
Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 2
Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients
Migraine
Aspeya, Inc.108 enrolled6 locationsNCT07646613
Recruiting
Phase 2
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8+1 more
Roswell Park Cancer Institute23 enrolled3 locationsNCT04348747
Recruiting
Phase 2
Phase II Clinical Study of the Efficacy and Safety of HSK55718 in the Treatment of Abdominal Postoperative Pain
Pain After Abdominal Surgery
Yingyong Zhou,MD,PhD200 enrolled2 locationsNCT07491146
Recruiting
Phase 2
Palbociclib and Pembrolizumab In Central Nervous System Metastases
Metastatic Malignant Neoplasm to BrainRecurrent Brain MetastasesProgressive Brain Metastases
Massachusetts General Hospital45 enrolled2 locationsNCT02896335
Recruiting
Phase 1Phase 2
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Brain CancerGBMGlioma+12 more
National Institute of Neurological Disorders and Stroke (NINDS)40 enrolled1 locationNCT07416188
Recruiting
Phase 2
Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
Brain MetastasesNonsmall Cell Lung Cancer Stage III
Wake Forest University Health Sciences60 enrolled1 locationNCT05692635
Recruiting
Phase 2
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 2
Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
Chronic Migraine
St. Olavs Hospital300 enrolled6 locationsNCT06485336
Recruiting
Phase 1Phase 2
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Colorectal, CancerEsophageal CancerGastric Cancer+18 more
Neonc Technologies, Inc.134 enrolled7 locationsNCT06047379
Recruiting
Phase 2
A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)
Metastatic Solid TumorBrain Metastases
M.D. Anderson Cancer Center30 enrolled1 locationNCT05673928
Recruiting
Phase 2
Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype
PainSleepMultiple Sclerosis
Tiffany J. Braley, MD, MS166 enrolled1 locationNCT05269628
Recruiting
Phase 2
Combined THC and CBD for OUD and Chronic Pain
Chronic PainOpioid-use Disorder
Yale University147 enrolled1 locationNCT06544291
Recruiting
Phase 2
Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy
Malignant Brain Neoplasm
Mayo Clinic100 enrolled1 locationNCT06377696