Amyloid Clinical Trials in London
16 recruitingLondon, United Kingdom
Showing 1–16 of 16 trials
Recruiting
Phase 2
A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy
Alnylam Pharmaceuticals200 enrolled57 locationsNCT06393712
Recruiting
Phase 1Phase 2
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Relapsed/Refractory Systemic Light Chain Amyloidosis
Regeneron Pharmaceuticals220 enrolled19 locationsNCT06292780
Recruiting
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
ATTR Amyloidosis
AstraZeneca52,121 enrolled26 locationsNCT06355934
Recruiting
Phase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled289 locationsNCT07207811
Recruiting
Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled207 locationsNCT07052903
Recruiting
Phase 1
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
Relapsed or Refractory Multiple MyelomaPreviously Treated Amyloid Light-chain (AL) Amyloidosis
Janssen Research & Development, LLC180 enrolled29 locationsNCT05652335
Recruiting
Phase 1
Test-retest Study With [18F]FBB in Cardiac Amyloidosis
Cardiac Amyloidosis
Life Molecular Imaging GmbH15 enrolled2 locationsNCT06790394
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Phase 1Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
AmyloidosisLight Chain AmyloidosisRelapsed AL Amyloidosis+1 more
Alexion Pharmaceuticals, Inc.91 enrolled18 locationsNCT07081646
Recruiting
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more
AstraZeneca1,850 enrolled53 locationsNCT06465810
Recruiting
Phase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting
Phase 1
A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK
Alzheimer DiseaseAutosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder)+1 more
University College, London10 enrolled2 locationsNCT06372821
Recruiting
Phase 1Phase 2
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Beta-AmyloidProdromal Alzheimer's DiseaseAmyloid Plaque+1 more
AC Immune SA176 enrolled19 locationsNCT05462106
Recruiting
Phase 3
Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis
AL AmyloidosisCardiac AmyloidosisATTR Amyloidosis
Life Molecular Imaging GmbH200 enrolled14 locationsNCT05184088
Recruiting
Not Applicable
PATHWAY-RCT: Preventing Admission To Hospital With Attr cardiomyopathY
Cardiac Amyloidosis
Richmond Research Institute320 enrolled1 locationNCT05098665
Recruiting
Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001
Transthyretin-Related (ATTR) Familial Amyloid CardiomyopathyTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics72 enrolled4 locationsNCT05697861