Astigmatism Clinical Trials

29 recruitingLast updated: June 20, 2026

There are 29 actively recruiting astigmatism clinical trials across 12 countries. Studies span Not Applicable, Phase 4. Top locations include Palo Alto, California, United States, Tianjin, Tianjin Municipality, China, Columbus, Ohio, United States. Updated daily from ClinicalTrials.gov.


Astigmatism Trials at a Glance

29 actively recruiting trials for astigmatism are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Palo Alto, Tianjin, and Columbus. Lead sponsors running astigmatism studies include Biotech Healthcare Holding Gmbh, CooperVision International Limited (CVIL), and Essilor International.

Browse astigmatism trials by phase

Treatments under study

About Astigmatism Clinical Trials

Looking for clinical trials for Astigmatism? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Astigmatism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Astigmatism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Not Applicable

Clareon TruPlus Study

AstigmatismAphakia
Alcon Research122 enrolled5 locationsNCT07502456
Recruiting
Not Applicable

Nomogram for Astigmatism Correction of KLEx

Astigmatism
Tianjin Eye Hospital100 enrolled1 locationNCT07605221
Recruiting
Not Applicable

Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day

Astigmatism
Ohio State University40 enrolled1 locationNCT07303920
Recruiting

Comfort and Vision With TOTAL30 Multifocal Lenses

MyopiaAstigmatismPresbyopia
Scripps Poway Eyecare and Optometry36 enrolled1 locationNCT07284966
Recruiting
Not Applicable

Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism

Astigmatism Bilateral
Ohio State University60 enrolled1 locationNCT06751225
Recruiting
Not Applicable

Improving Visual Quality in Patients With Irregular Corneas Using Asymmetrical Toric Intraocular Lenses

AstigmatismCataract and IOL SurgeryIrregular Astigmatism
Johannes Kepler University of Linz15 enrolled1 locationNCT07294716
Recruiting
Not Applicable

Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery

MyopiaAstigmatism
Stanford University70 enrolled1 locationNCT07078799
Recruiting
Phase 4

Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

Astigmatism
Center For Sight60 enrolled2 locationsNCT07140653
Recruiting
Not Applicable

A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery

AstigmatismCataractPresbyopia Correction
Biotech Healthcare Holding Gmbh138 enrolled6 locationsNCT07232615
Recruiting

Clinical Evaluation of WaveLight Plus LASIK

MyopiaAstigmatism
Laser Defined Vision50 enrolled1 locationNCT07127757
Recruiting
Not Applicable

A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism

MyopiaAstigmatism
Hoopes Vision120 enrolled1 locationNCT07201298
Recruiting

Patient Reported Outcomes With WaveLight Plus LASIK

MyopiaAstigmatism
Mann Eye Institute52 enrolled1 locationNCT07084844
Recruiting

North American Comfilcon A Clinical Study

AstigmatismPresbyopiaAmetropia
CooperVision International Limited (CVIL)182 enrolled4 locationsNCT06902584
Recruiting
Not Applicable

Effect of Corneal and Scleral RGP Lenses on Ocular Health and Visual Quality in Keratoconus

KeratoconusIrregular Astigmatism
University of Aarhus50 enrolled1 locationNCT06921967
Recruiting

Effectiveness, Stability and Influence Factors of Femtosecond Laser Assisted Cataract Surgery

corneal astigmatismCataract
Eye & ENT Hospital of Fudan University105 enrolled1 locationNCT07081919
Recruiting
Not Applicable

Algorithm-assisted Subjective Refraction Program Dedicated to Children

AstigmatismChildrenRefractive Disorders+3 more
Essilor International166 enrolled1 locationNCT07046065
Recruiting
Not Applicable

KLEx Versus FS-LASIK for the Treatment of Myopia and Compound Myopic Astigmatism

Myopic AstigmatismMyopiaAstigmatism
Instituto de Oftalmología Fundación Conde de Valenciana80 enrolled1 locationNCT06477081
Recruiting
Not Applicable

Rotation of Hydrophobic Acrylic Lenses - Rayner RA0800C & Alcon Clareon & Hoya Nanex & Hoya Vivinex XY1-EM & RayOne EMV Toric & PODEYE Toric

AstigmatismAge Related Cataracts
Medical University of Vienna750 enrolled1 locationNCT03803852
Recruiting
Not Applicable

The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.

AmetropiaMyopia; Refractive ErrorMyopia; Astigmatism
Essilor International315 enrolled2 locationsNCT06882408
Recruiting
Not Applicable

Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism

MyopiaAstigmatismHyperopia
CooperVision International Limited (CVIL)30 enrolled1 locationNCT06873048