Phase 2 Atherosclerosis Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

Atherosclerosis
Genentech, Inc.162 enrolled5 locationsNCT07448038
Recruiting
Phase 2

Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis

ASCVDAtherosclerosis Cardiovascular DiseaseASCVD Management
Atom Therapeutics Co., Ltd200 enrolled33 locationsNCT07303777
Recruiting
Phase 2

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting
Phase 2

Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

Cardiovascular DiseasesAtherosclerosisLipid Disorder+1 more
Wake Forest University Health Sciences130 enrolled1 locationNCT06488105
Recruiting
Phase 2Phase 3

Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis

Stroke, IschemicIntracranial Atherosclerosis
National University of Singapore130 enrolled1 locationNCT07282041
Recruiting
Phase 2

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

Cardiovascular DiseasesHIV InfectionsAtherosclerosis+1 more
Priscilla Hsue, MD121 enrolled3 locationsNCT05488431
Recruiting
Phase 2

[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease

Atherosclerosis Cardiovascular DiseaseStroke (CVA) or TIACarotid Artery Plaque+1 more
Universitaire Ziekenhuizen KU Leuven24 enrolled1 locationNCT07104487
Recruiting
Phase 2

A study to assess the safety and tolerability of BRB-002 in adults with established atherosclerosis

Atherosclerosis
Bitterroot Bio Australia Pty Ltd52 enrolled1 locationACTRN12625000273482
Recruiting
Phase 2

Evaluating the Impact of 'Tertinat' on Patients with Atherosclerosis-Related Cardiovascular Diseases

AtherosclerosisAtheroscleroses, Coronary
Institute for Atherosclerosis Research, Russia556 enrolled1 locationNCT06590012
Terminated
Phase 2

Can Semaglutide or empagliflozin stabilise coronary atherosclerosis in people with type 2 diabetes after acute coronary syndrome

Coronary atherosclerosis
South Australian Health and Medical Research Institute132 enrolled1 locationACTRN12623000661673
Recruiting
Phase 2Phase 3

Do stAtins faVourably modify atherosclerotIc plaque in patients with differeNt levels of polygenic Cardiovascular (CV) rIsk?

Coronary atherosclerosisPolygenic risk
Monash University600 enrolled6 locationsACTRN12620001166965