Atherosclerosis Clinical Trials

73 recruiting

Atherosclerosis Trials at a Glance

114 actively recruiting trials for atherosclerosis are listed on ClinicalTrialsFinder across 6 cities in 52 countries. The largest study group is Not Applicable with 32 trials, with the heaviest enrollment activity in Bethesda, Seoul, and Amsterdam. Lead sponsors running atherosclerosis studies include Xuanwu Hospital, Beijing, National Heart, Lung, and Blood Institute (NHLBI), and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse atherosclerosis trials by phase

Treatments under study

About Atherosclerosis Clinical Trials

Looking for clinical trials for Atherosclerosis? There are currently 73 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Atherosclerosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Atherosclerosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 114 trials

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

ObesityCardiomyopathyLi-Fraumeni Syndrome+3 more
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled3 locationsNCT01143454
Recruiting

Florbetaben for Imaging of Vascular Amyloid

StrokeAcute Coronary SyndromeTransient Ischemic Attack+1 more
Ottawa Heart Institute Research Corporation30 enrolled1 locationNCT06091319
Recruiting

Causes and Natural History of Dyslipidemias

AtherosclerosisHypercholesterolemia
National Heart, Lung, and Blood Institute (NHLBI)2,000 enrolled1 locationNCT00353782
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

Atherosclerosis
Genentech, Inc.162 enrolled5 locationsNCT07448038
Recruiting
Phase 2

Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis

ASCVDAtherosclerosis Cardiovascular DiseaseASCVD Management
Atom Therapeutics Co., Ltd200 enrolled33 locationsNCT07303777
Recruiting
Not Applicable

Radial vs Vena No-Touch Assessment

Coronary Artery Atherosclerosis
Tomsk Cardiology Research Institute110 enrolled1 locationNCT07552948
Recruiting
Phase 4

The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic Plaques

Stroke, IschemicAtherosclerosis, Cerebral
General Hospital of Shenyang Military Region100 enrolled1 locationNCT03753555
Recruiting

Oral Microbiome in Carotid Atherosclerosis

PeriodontitisAtherosclerosis Cardiovascular DiseaseAtherosclerosis of Artery+2 more
Semmelweis University Heart and Vascular Center200 enrolled1 locationNCT07296965
Recruiting

Evaluation of a Diagnostic Software for Coronary Artery Disease Using Retrospective CCTA Data (CODEX-1 Study)

AtherosclerosisMyocardial IschemiaCoronary Artery Disease
Instituto de Investigación Biomédica de Salamanca1,000 enrolled4 locationsNCT06977295
Recruiting
Not Applicable

New Heart Imaging Techniques to Evaluate Possible Heart Disease

ObesityHealthyDiabetes+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)4,000 enrolled1 locationNCT01399385
Recruiting
Phase 3

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

Chronic Kidney DiseaseAtherosclerosis Cardiovascular Disease
Eli Lilly and Company7,140 enrolled568 locationsNCT07241390
Recruiting
Early Phase 1

A Clinical Study of IMC-001 for Injection in Improving Atherosclerotic Plaque Stability in Patients With Acute Coronary Syndrome.

Atherosclerosis
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.18 enrolled2 locationsNCT06788431
Recruiting

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

CancerInsulin ResistanceMetabolic Syndrome+2 more
National Institute of Environmental Health Sciences (NIEHS)725 enrolled1 locationNCT01143480
Recruiting
Phase 2

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

Cardiovascular DiseaseSystemic Lupus ErythematosusPremature Atherosclerosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)45 enrolled1 locationNCT05440422
Recruiting

T-Mem GEne in Atherosclerosis

Atherosclerosis
IRCCS Policlinico S. Donato12 enrolled1 locationNCT06230406
Recruiting

Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access

Peripheral Arterial DiseaseAortic DiseasesAorto-Iliac Atherosclerosis
EndoCore Lab s.r.l.40 enrolled6 locationsNCT05880641
Recruiting
Not Applicable

Cardiac Rehabilitation and Coronary Artery Disease

AtherosclerosisCoronary Artery Disease
Instituto Nacional de Cardiologia de Laranjeiras50 enrolled1 locationNCT06579807
Recruiting

Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions

AtherosclerosisDyslipidemia
National Heart, Lung, and Blood Institute (NHLBI)1,500 enrolled1 locationNCT06676046
Recruiting
Phase 3

Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction

Coronary Artery DiseaseAcute Myocardial Infarction (AMI)Coronary Atherosclerosis of Native Coronary Artery
ECRI bv332 enrolled1 locationNCT07276282
Recruiting
Phase 3

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

Peripheral Arterial DiseaseInflammationAtherosclerosis of Extremities
Population Health Research Institute6,150 enrolled70 locationsNCT04774159