Atherosclerosis Clinical Trials

135 recruitingLast updated: June 17, 2026

There are 135 actively recruiting atherosclerosis clinical trials across 55 countries. Studies span Not Applicable, Phase 3, Phase 4, Phase 2, Early Phase 1, Phase 1. Top locations include Seoul, South Korea, Shanghai, China, Amsterdam, Netherlands. Updated daily from ClinicalTrials.gov.


Atherosclerosis Trials at a Glance

135 actively recruiting trials for atherosclerosis are listed on ClinicalTrialsFinder across 6 cities in 55 countries. The largest study group is Not Applicable with 42 trials, with the heaviest enrollment activity in Seoul, Shanghai, and Amsterdam. Lead sponsors running atherosclerosis studies include Xuanwu Hospital, Beijing, Maastricht University Medical Center, and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse atherosclerosis trials by phase

Treatments under study

About Atherosclerosis Clinical Trials

Looking for clinical trials for Atherosclerosis? There are currently 77 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Atherosclerosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Atherosclerosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 135 trials

Recruiting

Causes and Natural History of Dyslipidemias

AtherosclerosisHypercholesterolemia
National Heart, Lung, and Blood Institute (NHLBI)2,000 enrolled1 locationNCT00353782
Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

ObesityCardiomyopathyLi-Fraumeni Syndrome+3 more
National Heart, Lung, and Blood Institute (NHLBI)5,000 enrolled3 locationsNCT01143454
Recruiting
Not Applicable

Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD

Cardiovascular DiseasesAtherosclerosisDyslipidemia+2 more
Yonsei University1,952 enrolled1 locationNCT07524101
Recruiting

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

CancerInsulin ResistanceMetabolic Syndrome+2 more
National Institute of Environmental Health Sciences (NIEHS)725 enrolled1 locationNCT01143480
Recruiting
Phase 4

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

Atherosclerotic PlaqueIntracranial AtherosclerosisIntracranial Artery Stenosis
Peking Union Medical College Hospital300 enrolled19 locationsNCT06902740
Recruiting
Not Applicable

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

AtherosclerosisCoronary Artery DiseaseCoronary Atherosclerosis of Native Coronary Artery
Johns Hopkins University33 enrolled1 locationNCT05994014
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

Atherosclerosis
Genentech, Inc.162 enrolled11 locationsNCT07448038
Recruiting
Not Applicable

Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History

AtherosclerosisAir Pollution
University of Southern California112 enrolled1 locationNCT05867381
Recruiting
Not Applicable

New Heart Imaging Techniques to Evaluate Possible Heart Disease

ObesityHealthyDiabetes+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)4,000 enrolled1 locationNCT01399385
Recruiting
Phase 3

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

Chronic Kidney DiseaseAtherosclerosis Cardiovascular Disease
Eli Lilly and Company7,140 enrolled568 locationsNCT07241390
Recruiting
Not Applicable

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

StressAtherosclerosisInflammation
Massachusetts General Hospital30 enrolled1 locationNCT04496947
Recruiting
Phase 4

SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes

AtherosclerosisType 2 Diabetes Mellitus (T2DM)Coronary Artery Disease
Junjie Yang144 enrolled2 locationsNCT07614230
Recruiting
Phase 4

Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)

Psoriatic Arthritis (PsA)AtherosclerosisRheumatoid Arthritis (RA)+4 more
Instituto de Investigación Marqués de Valdecilla1,944 enrolled17 locationsNCT07611747
Recruiting
Not Applicable

Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation

Stroke, IschemicStrokeStroke (CVA) or TIA+7 more
Maastricht University Medical Center613 enrolled10 locationsNCT07556887
Recruiting

Translational Immunodiagnostics in Stroke (TrImS)

Atrial FibrillationAcute Ischemic StrokeCardioembolic Stroke+9 more
The University of Hong Kong650 enrolled1 locationNCT05300997
Recruiting
Not Applicable

High Protein Diet and Atherosclerosis

Atherosclerosis
University of Missouri-Columbia24 enrolled1 locationNCT05235464
Recruiting

Florbetaben for Imaging of Vascular Amyloid

StrokeAcute Coronary SyndromeTransient Ischemic Attack+1 more
Ottawa Heart Institute Research Corporation30 enrolled1 locationNCT06091319
Recruiting
Phase 4

Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia

Diabetes Mellitus, Type 2AtherosclerosisDyslipidemias
Seoul National University Bundang Hospital105 enrolled1 locationNCT05365438
Recruiting
Phase 4

Clopidogrel Versus Cilostazol on Vessels

AtherosclerosisType 2 Diabetes
Seoul National University Bundang Hospital120 enrolled1 locationNCT06402747
Recruiting
Phase 4

Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia

Diabetes Mellitus, Type 2AtherosclerosisDyslipidemia
Seoul National University Bundang Hospital56 enrolled1 locationNCT05365425