Phase 2 Bipolar Clinical Trials
23 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 23 trials
Recruiting
Phase 2
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder
Bipolar 1 Disorder
Rapport Therapeutics Inc.224 enrolled22 locationsNCT07046494
Recruiting
Phase 2
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
Bipolar Disorder
Eli Lilly and Company400 enrolled88 locationsNCT07286175
Recruiting
Phase 1Phase 2
Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine
SchizophreniaMajor Depressive DisorderBipolar I Disorder
Mapi Pharma Ltd.24 enrolled6 locationsNCT07185815
Recruiting
Phase 1Phase 2
A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder
Bipolar I Disorder
Alzamend Neuro, Inc.20 enrolled1 locationNCT07540338
Recruiting
Phase 2
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
Bipolar I Disorder
LB Pharmaceuticals Inc.320 enrolled3 locationsNCT07494305
Recruiting
Phase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
Bipolar I DisorderBipolar II Disorder
AbbVie195 enrolled29 locationsNCT06696755
Recruiting
Phase 2
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
Bipolar I or II Disorder
AbbVie200 enrolled49 locationsNCT07220460
Recruiting
Phase 2
Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
Bipolar Disorder
Mclean Hospital25 enrolled1 locationNCT05457465
Recruiting
Phase 2
An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania
Bipolar I DisorderMania
Neurocrine Biosciences150 enrolled6 locationsNCT07288320
Recruiting
Phase 1Phase 2
Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian
Bipolar Disorder (BD)
Babes-Bolyai University50 enrolled1 locationNCT07399626
Recruiting
Phase 2
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Depression, AnxietyStressBipolar I Disorder
Mclean Hospital40 enrolled1 locationNCT05837104
Recruiting
Phase 2
Study of ABX-002 for the Adjunctive Treatment of Depressive Episodes Associated With Bipolar Disorder in Adults
Bipolar Disorder Depression
Autobahn Therapeutics, Inc.35 enrolled15 locationsNCT06869187
Recruiting
Phase 2
Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
Bipolar Disorder
Leslie Swanson50 enrolled1 locationNCT06226025
Recruiting
Phase 2
BezafibrateTreatment for Bipolar Depression: A Proof of Concept Study
Bipolar DisorderDepressive Episode
Massachusetts General Hospital30 enrolled1 locationNCT02481245
Recruiting
Phase 2Phase 3
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
Suicidal IdeationMajor Depressive DisorderBipolar Disorder+1 more
Michigan State University30 enrolled1 locationNCT06529029
Recruiting
Phase 2
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
Bipolar II Disorder
The University of Texas Health Science Center, Houston10 enrolled1 locationNCT06706232
Recruiting
Phase 2
ALTO-100 in Bipolar Disorder With Depression (BD-D)
Bipolar Disorder I or II With a Major Depressive Episode
Alto Neuroscience200 enrolled27 locationsNCT06656416
Recruiting
Phase 2
Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
Cannabis UseBipolar DisorderSchizoaffective Disorder, Bipolar Type+5 more
Medical University of South Carolina68 enrolled1 locationNCT05064319
Recruiting
Phase 1Phase 2
Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
Bipolar Depression
Laureate Institute for Brain Research, Inc.20 enrolled1 locationNCT06088732
Not Yet Recruiting
Phase 2
Oral ketamine for bipolar depression
Bipolar Disorder
University of Otago30 enrolled1 locationACTRN12625000267459