Phase 3 Bladder Cancer Clinical Trials
19 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–19 of 19 trials
Recruiting
Phase 3
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Bladder Cancer
Merck Sharp & Dohme LLC590 enrolled21 locationsNCT07419295
Recruiting
Phase 3
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Intermediate Risk Non-Muscle Invasive Bladder Cancer
Ferring Pharmaceuticals454 enrolled82 locationsNCT06510374
Recruiting
Phase 3
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer
Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Ferring Pharmaceuticals250 enrolled66 locationsNCT06545955
Recruiting
Phase 3
Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy
Stage 0a Bladder Cancer AJCC v8Stage I Bladder Cancer AJCC v8Recurrent Non-Muscle Invasive Bladder Carcinoma
Alliance for Clinical Trials in Oncology330 enrolled56 locationsNCT07000084
Recruiting
Phase 3
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
NRG Oncology486 enrolled211 locationsNCT07097142
Recruiting
Phase 3
Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients With Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC)
Bladder CancerUrothelial Carcinoma BladderNeoplasm Recurrence+3 more
Verity Pharmaceuticals Inc.540 enrolled6 locationsNCT05037279
Recruiting
Phase 2Phase 3
Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma
Urothelial CancerBladder Cancer
Daiichi Sankyo630 enrolled79 locationsNCT07129993
Recruiting
Phase 3
A Study of Surgical Techniques During Cystectomy
Bladder Cancer
Memorial Sloan Kettering Cancer Center530 enrolled7 locationsNCT06703476
Recruiting
Phase 2Phase 3
Trop2-targeted immunoPET Imaging of Solid Tumors
Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 3
The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
Bladder CancerEndometriosisInterstitial Cystitis+4 more
Centre Hospitalier Universitaire Vaudois232 enrolled4 locationsNCT05726786
Recruiting
Phase 3
Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection
Bladder Cancer
Johns Hopkins University200 enrolled2 locationsNCT06525571
Recruiting
Phase 3
Treatment Expedition With MRI Processing and Optimization for Muscle Invasive Bladder Cancer
Bladder CarcinomaBladder NeoplasmMuscle Invasive Bladder Cancer (MIBC)+2 more
University of Rome Tor Vergata92 enrolled1 locationNCT07067749
Recruiting
Phase 3
Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL)
Bladder CancerBladder Urothelial Carcinoma
University Health Network, Toronto14 enrolled2 locationsNCT04574960
Recruiting
Phase 2Phase 3
Clinical Study on the Treatment of MIBC Patients With SHR-A2102 Injection Combined With Adebrelimab (SHR-1316)
Muscular Invasive Bladder Cancer (MIBC)
Suzhou Suncadia Biopharmaceuticals Co., Ltd.840 enrolled1 locationNCT06879145
Recruiting
Phase 2Phase 3
Radiation Therapy in Unresectable Gall Bladder Cancer
Gall Bladder Cancer
Tata Memorial Centre249 enrolled1 locationNCT06214572
Recruiting
Phase 3
Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC Patients
Non-Muscle-Invasive Bladder Cancer (NMIBC)
Shaogang Wang180 enrolled3 locationsNCT06696794
Recruiting
Phase 2Phase 3
Addition of Everolimus to Standard of Care in Carcinoma Gallbladder
Gallbladder Cancer
Banaras Hindu University56 enrolled1 locationNCT05833815
Recruiting
Phase 3
Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
Bladder Cancer
Brigham and Women's Hospital136 enrolled1 locationNCT03216525
Recruiting
Phase 3
Effectiveness of an Immediate Postoperative Intravesical Instillation With Either Gemcitabine or Epirubicin in Patients With Urinary Bladder Cancer (Gemcitabine Epirubicin Normal SAline)
Bladder Cancer
University of Thessaly180 enrolled1 locationNCT04947059