Brain Injuries Clinical Trials

51 recruitingLast updated: June 18, 2026

There are 51 actively recruiting brain injuries clinical trials across 19 countries. Studies span Not Applicable, Phase 4, Phase 3. Top locations include San Francisco, California, United States, Toronto, Ontario, Canada, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Brain Injuries Trials at a Glance

51 actively recruiting trials for brain injuries are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 23 trials, with the heaviest enrollment activity in San Francisco, Toronto, and Boston. Lead sponsors running brain injuries studies include All India Institute of Medical Sciences, Jodhpur, Assistance Publique - Hôpitaux de Paris, and A/Prof Ian Baguley.

Browse brain injuries trials by phase

Treatments under study

About Brain Injuries Clinical Trials

Looking for clinical trials for Brain Injuries? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain Injuries trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain Injuries clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 51 trials

Recruiting

Socio-Cultural Level, Health Literacy, and Parental CT Demand in Paediatric Minor Head Trauma: A Prospective Cohort Study

Brain Injuries, TraumaticHead Injuries, ClosedCraniocerebral Trauma
Bursa Yuksek Ihtisas Training and Research Hospital200 enrolled1 locationNCT07655310
Recruiting

Automated Robotic TCD in Traumatic Brain Injury

Brain Injuries, Traumatic
Virginia Commonwealth University30 enrolled3 locationsNCT05848297
Recruiting

Recovery Trajectory for Coma and Disorders of Consciousness

Traumatic Brain InjuriescomaDisorders of Consciousness+5 more
University of California, San Francisco2,000 enrolled1 locationNCT07614074
Recruiting

mTBI Identification and Monitoring Through Retinal Scanning

Brain Injuries, Traumatic
Rebiscan, Inc.60 enrolled1 locationNCT06142435
Recruiting
Not Applicable

Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function

SleepInflammationGlymphatic System+3 more
Oregon Health and Science University300 enrolled1 locationNCT07601841
Recruiting
Not Applicable

Mild TBI Assessment & Rehabilitation

Brain Injuries, Traumatic
VA Office of Research and Development65 enrolled2 locationsNCT02920788
Recruiting
Phase 4

Buspirone and Melatonin for Depression Following Traumatic Brain Injury

DepressionBrain Injuries, Traumatic
Massachusetts General Hospital10 enrolled2 locationsNCT04400266
Recruiting

Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury

Mechanical VentilationAcute Brain Injuries
Southeast University, China1,500 enrolled1 locationNCT07496125
Recruiting
Not Applicable

The Impact of Self-processing on Mental Time Travel

Brain Injuries, Focal
Istituti Clinici Scientifici Maugeri SpA66 enrolled1 locationNCT06823193
Recruiting
Not Applicable

Brain Injury Education and Outpatient Navigation-1stBIEN

RehabilitationBrain Injuries, Traumatic
Seattle Children's Hospital300 enrolled6 locationsNCT05261477
Recruiting
Not Applicable

Brain Oxygen Optimization in Severe TBI, Phase 3

Brain Injuries, Traumatic
University of Michigan1,094 enrolled54 locationsNCT03754114
Recruiting
Not Applicable

Comparison of Ultrasound Cerebral Perfusion Imaging With Routine Perfusion CT

Cerebral IschemiaNeurological ComplicationNeuro ICU+2 more
Resolve Stroke50 enrolled1 locationNCT07324421
Recruiting
Not Applicable

The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms

Brain Injuries
The University of Texas Medical Branch, Galveston130 enrolled1 locationNCT06607523
Recruiting
Not Applicable

Biomarker Role in Assessing Imaging Needs for Mild Cranial Trauma

Brain InjuriesHead Injury
Emory University350 enrolled1 locationNCT06932588
Recruiting
Phase 3

The NIPA Study Naloxegol Administration to Prevent Opioids Induced Gastrointestinal Motility Disturbance in Brain Injured PAtients

Brain Injuries
University Hospital, Brest370 enrolled11 locationsNCT05008926
Recruiting
Not Applicable

Morning Bright Light to Improve Sleep Quality in Veterans

Post Traumatic Stress DisorderBrain Injuries, Traumatic
Portland VA Medical Center200 enrolled1 locationNCT03578003
Recruiting
Not Applicable

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Brain TraumaNeurocognitive DysfunctionMild Cognitive Impairment+8 more
United States Naval Medical Center, San Diego160 enrolled2 locationsNCT06413173
Recruiting
Not Applicable

Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

Traumatic Brain InjuryCerebral PalsySpinal Cord Injuries+3 more
University of Pittsburgh160 enrolled1 locationNCT02592291
Recruiting

Screening Emotions in Adolescents at the Hospital for mTBI

Diffuse axonal injuryBrain InjuriesIntracranial Hemorrhages+7 more
University of California, Davis2,592 enrolled6 locationsNCT06370520
Recruiting
Not Applicable

Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study

Muscle SpasticityTraumatic Brain InjuriesStroke+1 more
Vastra Gotaland Region30 enrolled1 locationNCT06733025