Phase 2 Brain Injury Clinical Trials

39 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 39 trials

Recruiting
Phase 2

Feasibility and Safety of Targeting Neutral vs Liberal Fluid Balance in Traumatic Brain Injured Patients- LIMIT-TBI Trial

Acute brain injuryTraumatic Brain InjuryNeurocritical Care+1 more
Erasme University Hospital88 enrolled3 locationsNCT07625995
Recruiting
Phase 2

Hyperbaric Oxygen Brain Injury Treatment Trial

Traumatic Brain Injury
Gaylan Rockswold200 enrolled11 locationsNCT02407028
Recruiting
Phase 2

Vitamin D3 for Moderate to Mild Traumatic Brain Injury: A Randomized Trial on Inflammation and Recovery (VIMOT)

NeuroinflammationTraumatic Brain Injury (TBI) Patients
Lagos State University240 enrolled1 locationNCT07269457
Recruiting
Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 2

Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/Contusions

Traumatic Brain Injury
Tang-Du Hospital100 enrolled1 locationNCT06065046
Recruiting
Phase 2

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

DepressionAnxietyDysautonomia+9 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting
Phase 2

Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI

Traumatic Brain InjuryPost Traumatic Stress Disorder
NYU Langone Health120 enrolled1 locationNCT04550377
Recruiting
Phase 1Phase 2

Low-Tech Treatments for Obstructive Sleep Apnea

Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Phase 2Phase 3

FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial

Moderate to severe traumatic brain injury
Northwestern University357 enrolled1 locationNCT06062888
Recruiting
Phase 2

Assessment of Noninvasive Neuromodulation in a Group of Traumatic Brain Injured Patients and Healthy Volunteers

Traumatic Brain Injury
University of Sao Paulo60 enrolled1 locationNCT07373366
Recruiting
Phase 2

Antisecretory Factor In Severe Traumatic Brain Injury

Traumatic Brain Injury
Peter Siesjö20 enrolled1 locationNCT04117672
Recruiting
Phase 2

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

Traumatic Brain Injury
University of Cincinnati72 enrolled1 locationNCT05337618
Recruiting
Phase 2

Sildenafil for Microvasculopathy in Chronic TBI

Traumatic Brain Injury
University of Pennsylvania160 enrolled1 locationNCT05782244
Not Yet Recruiting
Phase 2

Alternative Fuels for Traumatic Brain Injury project (Phase 2)

Traumatic Brain Injury
East Metropolitan Health Service30 enrolled1 locationACTRN12625001249448
Recruiting
Phase 2

Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

PTSD - Post Traumatic Stress DisorderTBI (Traumatic Brain Injury)Post Concussive Syndrome
Summit Hyperbarics and Wellness54 enrolled1 locationNCT07214415
Recruiting
Phase 2

Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

Traumatic Brain Injury
Hope Biosciences LLC51 enrolled2 locationsNCT05951777
Recruiting
Phase 2Phase 3

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

Post Traumatic Stress DisorderMild Traumatic Brain InjuryAutonomic Nervous System Disease+2 more
Virginia Commonwealth University148 enrolled1 locationNCT07071350
Recruiting
Phase 2

Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)

Traumatic Brain Injury
University of Miami50 enrolled1 locationNCT06293300
Recruiting
Phase 1Phase 2

Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury

Traumatic Brain Injury
University of Arizona90 enrolled1 locationNCT06282965
Recruiting
Phase 1Phase 2

Evaluating the Impact of Adjuvant Use of Beta Blockers on Clinical Outcomes in Patients With Traumatic Brain Injury

TBI (Traumatic Brain Injury)
Mansoura University100 enrolled2 locationsNCT06836856