Phase 4 Brain Clinical Trials
25 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 25 trials
Recruiting
Phase 4
Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide
Traumatic Brain Injury
Wake Forest University Health Sciences600 enrolled1 locationNCT06866691
Recruiting
Phase 4
Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation
Endothelial DysfunctionIschemic StrokeCerebrovascular Event+4 more
Duan Chuanzhi354 enrolled1 locationNCT06308952
Recruiting
Phase 4
An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center10 enrolled1 locationNCT05376878
Recruiting
Phase 4
Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities
Multiple SclerosisSpinal Cord InjuryCentreal Neurological Condition+1 more
Oxford University Hospitals NHS Trust50 enrolled1 locationNCT07303582
Recruiting
Phase 4
Modulation of the Brain Fog Scale by Eicosapentaenoic Acid Monoglycerides (MAG-EPA).
Brain Fog
Samuel Fortin48 enrolled2 locationsNCT06695910
Recruiting
Phase 4
Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
Breast CancerBrain Metastases
Weill Medical College of Cornell University20 enrolled1 locationNCT06072807
Recruiting
Phase 4
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
Traumatic Brain InjuryBrain Tumor AdultWound Closure+3 more
University of Michigan160 enrolled1 locationNCT07225101
Recruiting
Phase 4
Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive Outcome
Brain Edema Caused by DrugsCerebral Oxygenation
Georgia Tsaousi84 enrolled2 locationsNCT06779890
Recruiting
Phase 4
Imaging Biomarkers of FOG Response to DBS
Deep Brain StimulationFreezing of Gait Symptoms in Parkinson's Disease
Medical University of South Carolina54 enrolled1 locationNCT06951906
Recruiting
Phase 4
Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)
Traumatic Brain InjuriesSeizuresTraumatic Brain Injury (TBI) Patients
All India Institute of Medical Sciences, Jodhpur1,260 enrolled3 locationsNCT07072624
Recruiting
Phase 4
SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery
Endothelial DysfunctionBrain DiseaseVascular Diseases+2 more
Vanderbilt University Medical Center170 enrolled1 locationNCT05812755
Recruiting
Phase 4
The Analgesic Effect of Scalp Nerve Block Using Bupivacaine Liposomes for Postoperative Pain Relief After Craniotomy
Cerebrovascular DiseaseBrain Tumor Adult
Zhejiang University218 enrolled1 locationNCT07049094
Recruiting
Phase 4
Partial Oral Antibiotic Treatment for Bacterial Brain Abscess
Brain AbscessCerebral Abscess
Henrik Nielsen400 enrolled4 locationsNCT04140903
Recruiting
Phase 4
The Study of Ginkgo Leaf Dropping Pills and Huperzine a Injection Combined with Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain Injury
Cognitive Impairment After Brain Injury
Wanbangde Pharmaceutical Group Co., LTD50 enrolled1 locationNCT06704334
Recruiting
Phase 4
Ketamine in Acute Brain Injury Patients.
Brain Injuries, Traumatic
Geert Meyfroidt, MD, PhD100 enrolled8 locationsNCT05097261
Recruiting
Phase 4
The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Traumatic Brain InjuryIntracerebral HemorrhageSubarachnoid Hemorrhage, Aneurysmal
Rigshospitalet, Denmark400 enrolled1 locationNCT05095857
Recruiting
Phase 4
Buspirone and Melatonin for Depression Following Traumatic Brain Injury
DepressionBrain Injuries, Traumatic
Massachusetts General Hospital10 enrolled2 locationsNCT04400266
Recruiting
Phase 4
For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide.
Central Nervous System DiseasesStrokeNervous System Diseases+4 more
Qianfoshan Hospital300 enrolled1 locationNCT05068349
Recruiting
Phase 4
The Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of Action
Liver CancerOvarian CancerLung Cancer+1 more
Kaohsiung Medical University Chung-Ho Memorial Hospital1,316 enrolled1 locationNCT05926336
Completed
Phase 3Phase 4
A randomised double-blind placebo-controlled study to evaluate the effect of curcumin on BDNF levels in otherwise healthy adults.
Brain-Derived Neurotrophic Factor in healthy adults
RDC Global Pty Ltd70 enrolled1 locationACTRN12621000104853