Brain Clinical Trials

6 recruiting

Brain Trials at a Glance

995 actively recruiting trials for brain are listed on ClinicalTrialsFinder across 6 cities in 63 countries. The largest study group is Not Applicable with 394 trials, with the heaviest enrollment activity in Boston, Houston, and New York. Lead sponsors running brain studies include M.D. Anderson Cancer Center, Beijing Tiantan Hospital, and VA Office of Research and Development.

Treatments under study

About Brain Clinical Trials

Looking for clinical trials for Brain? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 995 trials

Recruiting

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

StrokeBrain DiseaseVascular Diseases+1 more
National Institute of Neurological Disorders and Stroke (NINDS)450 enrolled1 locationNCT06615973
Recruiting

Natural History of Stroke: Cause and Development

Brain DiseaseVascular DiseasesIschemic Attack, Transient+2 more
National Institute of Neurological Disorders and Stroke (NINDS)4,000 enrolled3 locationsNCT00009243
Recruiting

Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

AlcoholismAlcohol DrinkingAlcohol Dependence+2 more
National Institute on Alcohol Abuse and Alcoholism (NIAAA)1,000 enrolled1 locationNCT02108080
Recruiting
Not Applicable

Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.

Traumatic Brain Injury
NYU Langone Health150 enrolled1 locationNCT04349852
Recruiting

Study of New Magnetic Resonance Imaging Methods of the Brain

HealthyHealthy VolunteerAdult+3 more
National Institute of Neurological Disorders and Stroke (NINDS)1,100 enrolled1 locationNCT00004577
Recruiting
Not Applicable

Implementation of a Home-based Computerized Cognitive Rehabilitation Program for Patients With ABI

Acquired Brain Injury (Including Stroke)
Erasmus Medical Center30 enrolled1 locationNCT06749197
Recruiting

Tumor Related Epilepsy

CancerEpilepsyBrain Neoplasm
National Institute of Neurological Disorders and Stroke (NINDS)100 enrolled1 locationNCT02639325
Recruiting
Phase 1Phase 2

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

CancerBrain Tumor
National Cancer Institute (NCI)96 enrolled1 locationNCT05588141
Recruiting

A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

Traumatic Brain Injury
Hoffmann-La Roche2,000 enrolled12 locationsNCT07455136
Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Not Applicable

Feasibility of Web-based Therapy Sessions

Cognitive ImpairmentAcquired Brain InjurySpeech Dysfunction
Liverpool University Hospitals NHS Foundation Trust80 enrolled1 locationNCT07560696
Recruiting
Not Applicable

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Healthy VolunteerBrain Mapping
National Institute of Mental Health (NIMH)300 enrolled1 locationNCT01266577
Recruiting
Phase 2

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco96 enrolled5 locationsNCT07110246
Recruiting

Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders

MyoclonusNeurological RegressionCherry Red Spot+1 more
National Human Genome Research Institute (NHGRI)200 enrolled1 locationNCT00029965
Recruiting

Top-Down Attentional Control of Visual-Processing

fMRIFocal Brain LesionFocal Lesions
National Institute of Mental Health (NIMH)300 enrolled1 locationNCT01087281
Recruiting
Phase 2

Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique

Brain Metastases
Medical College of Wisconsin53 enrolled2 locationsNCT05045950
Recruiting
Not Applicable

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

DepressionMild Traumatic Brain InjuryConcussion, Brain
University of California, San Diego72 enrolled1 locationNCT05682677
Recruiting
Not Applicable

Non-invasive BCI-controlled Assistive Devices

Traumatic Brain InjuryHealthyMovement Disorders+6 more
University of Texas at Austin100 enrolled1 locationNCT05183152
Recruiting
Not Applicable

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

SleepMild Traumatic Brain InjurySleep Architecture+1 more
University of Missouri-Columbia15 enrolled1 locationNCT07385105
Recruiting
Phase 1Phase 2

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408