Cachexia Clinical Trials

21 recruiting

Cachexia Trials at a Glance

33 actively recruiting trials for cachexia are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Beijing, Portland, and Guangzhou. Lead sponsors running cachexia studies include Changchun GeneScience Pharmaceutical Co., Ltd., University of Edinburgh, and Academisch Ziekenhuis Maastricht.

Browse cachexia trials by phase

Treatments under study

About Cachexia Clinical Trials

Looking for clinical trials for Cachexia? There are currently 21 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cachexia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cachexia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting
Phase 2Phase 3

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Metastatic Pancreatic Ductal AdenocarcinomaCachexia
Pfizer982 enrolled114 locationsNCT06989437
Recruiting
Phase 1

A Clinical Study of Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer

CachexiaLocally Advanced Cervical Cancer
Second Xiangya Hospital of Central South University88 enrolled1 locationNCT07338487
Recruiting
Not Applicable

Nano-Megestrol Acetate for Cancer Cachexia in Advanced Pancreatic Cancer

Advanced Pancreatic Ductal AdenocarcinomaCancer Anorexia-Cachexia Syndrome
Shandong Cancer Hospital and Institute56 enrolled1 locationNCT07408505
Recruiting
Phase 2Phase 3

Visugromab in Cachexia International Trial

Cancer-associated Cachexia
CatalYm GmbH518 enrolled7 locationsNCT07112196
Recruiting
Not Applicable

Study on the Pathogenesis and Reversal Strategies of Cancer Cachexia Based on Multi-Omics

Cachexia; Cancer; Sarcopenia
China Medical University, China1,000 enrolled1 locationNCT07519837
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder

Cancer of the BreastCancerAdjustment Disorder+8 more
Psyence Australia Pty Ltd87 enrolled3 locationsNCT07072728
Recruiting

A First-in-Human Study of FID-022 in Solid Tumor Patients

Pancreatic CancerCancer Cachexia
H. Lee Moffitt Cancer Center and Research Institute120 enrolled1 locationNCT07249775
Recruiting

Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma

Pancreas AdenocarcinomaCachexia
Wake Forest University Health Sciences100 enrolled2 locationsNCT05376592
Recruiting
Not Applicable

Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases

CancerCancer CachexiaInflammation+1 more
University of Erlangen-Nürnberg Medical School100 enrolled1 locationNCT04067167
Recruiting
Phase 1

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

Cachexia
AVEO Pharmaceuticals, Inc.30 enrolled12 locationsNCT05865535
Recruiting
Phase 1

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of SXRN Injection in Patients With Cancer Cachexia

Solid Tumor MalignanciesCachexia-Anorexia Syndrome
Jiangsu Nutai Biologics Co., Ltd54 enrolled1 locationNCT07231120
Recruiting

REVOLUTION Surgery (REVOLUTION Surgery)

Pancreatic CancerGastric CancerOesophageal Cancer+1 more
University of Edinburgh200 enrolled1 locationNCT05642819
Recruiting
Phase 4

A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia

Clinical Characteristics and Treatment Outcomes of Malignant Tumor CachexiaMulticenter Observational Study
Changchun GeneScience Pharmaceutical Co., Ltd.495 enrolled1 locationNCT07243379
Recruiting
Phase 1

To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants

Cancer CachexiaCancer Cachexia (CC)
Shenzhen Kexing Pharmaceutical Co., Ltd.36 enrolled1 locationNCT07237464
Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Heart FailureSarcopeniaOsteoporosis+11 more
Bettina Mittendorfer100 enrolled1 locationNCT07083557
Recruiting

Influence of Protein Intake on Muscle Mass and Health-related Quality of Life During and After Radiotherapy

Malnutrition; Cachexia
Charite University, Berlin, Germany175 enrolled1 locationNCT06480266
Recruiting

Patient Recorded Indexing Measurements

CancerCachexiaWeight, Body
Academisch Ziekenhuis Maastricht300 enrolled2 locationsNCT05899205
Recruiting

Body Composition and Psychosocial Factors in ICI-Treated Cancer Patients

CancerTreatment Side EffectsCachexia+1 more
Hacettepe University200 enrolled1 locationNCT07130981
Recruiting

Routine Evaluation of People Living With Cancer

Advanced CancerQuality of LifeCachexia; Cancer
University of Edinburgh600 enrolled1 locationNCT04406662
Recruiting
Not Applicable

Evaluation of a High Protein Plant Dominant Diet (HiProPlaDo) in Liver Cirrhosis

SarcopeniaLiver DiseasesCirrhosis, Liver+1 more
Agricultural University of Athens100 enrolled2 locationsNCT07028580