Cachexia Clinical Trials

41 recruitingLast updated: June 18, 2026

There are 41 actively recruiting cachexia clinical trials across 33 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1, Phase 4. Top locations include Beijing, Beijing Municipality, China, Edinburgh, United Kingdom, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Cachexia Trials at a Glance

41 actively recruiting trials for cachexia are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Beijing, Edinburgh, and Baltimore. Lead sponsors running cachexia studies include Changchun GeneScience Pharmaceutical Co., Ltd., Jiangsu Nutai Biologics Co., Ltd, and University of Edinburgh.

Browse cachexia trials by phase

Treatments under study

About Cachexia Clinical Trials

Looking for clinical trials for Cachexia? There are currently 22 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cachexia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cachexia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 41 trials

Recruiting
Phase 2

Phase 2 Cachexia Clinical Trial to Evaluate the Efficacy and Safety of ASCA101

Cachexia; Cancer
MetaFines135 enrolled6 locationsNCT07168226
Recruiting
Phase 1

A Phase I Clinical Study to Evaluate the Efficacy and Safety of GB18 Injection in Patients With Tumor Cachexia

Cachexia; Cancer
Kexing Biopharm Co., Ltd.18 enrolled2 locationsNCT07519564
Recruiting
Phase 2Phase 3

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Metastatic Pancreatic Ductal AdenocarcinomaCachexia
Pfizer982 enrolled188 locationsNCT06989437
Recruiting
Phase 2Phase 3

Visugromab in Cachexia International Trial

Cancer-associated Cachexia
CatalYm GmbH518 enrolled35 locationsNCT07112196
Recruiting
Not Applicable

Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients

muscle wastingCancerResistance Training+3 more
University of Erlangen-Nürnberg Medical School288 enrolled1 locationNCT07643558
Recruiting
Phase 3

Olanzapine in the Prevention and Treatment of Anorexia-Cachexia Syndrome in Patients Receiving Neoadjuvant/Preoperative Chemotherapy

OncologyCachexia-Anorexia SyndromeOncology Patients Receiving Chemotherapy
Blokhin's Russian Cancer Research Center100 enrolled1 locationNCT07633236
Recruiting
Phase 1Phase 2

A Study of JMT203 in Patients With Cancer Cachexia

Pancreatic CancerNon-small Cell Lung CancerCancer Cachexia+2 more
Shanghai JMT-Bio Inc.307 enrolled1 locationNCT06868849
Recruiting
Early Phase 1

A Phase I Study on Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of SXRN Plasmid DNA Technique in Patients With Advanced Solid Tumors

Advanced CancerCachexia
Jiangsu Nutai Biologics Co., Ltd28 enrolled1 locationNCT06736275
Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Heart FailureSarcopeniaOsteoporosis+11 more
Bettina Mittendorfer100 enrolled1 locationNCT07083557
Recruiting
Not Applicable

Nano-Megestrol Acetate for Cancer Cachexia in Advanced Pancreatic Cancer

Advanced Pancreatic Ductal AdenocarcinomaCancer Anorexia-Cachexia Syndrome
Shandong Cancer Hospital and Institute56 enrolled1 locationNCT07408505
Recruiting
Phase 1

A Clinical Study of Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer

CachexiaLocally Advanced Cervical Cancer
Second Xiangya Hospital of Central South University88 enrolled1 locationNCT07338487
Recruiting
Not Applicable

Study on the Pathogenesis and Reversal Strategies of Cancer Cachexia Based on Multi-Omics

Cachexia; Cancer; Sarcopenia
China Medical University, China1,000 enrolled1 locationNCT07519837
Recruiting
Phase 2

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Colorectal, CancerCancer CachexiaCRC (Colorectal Cancer)
NGM Biopharmaceuticals, Inc136 enrolled28 locationsNCT07033026
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder

Cancer of the BreastCancerAdjustment Disorder+8 more
Psyence Australia Pty Ltd87 enrolled3 locationsNCT07072728
Recruiting

A First-in-Human Study of FID-022 in Solid Tumor Patients

Pancreatic CancerCancer Cachexia
H. Lee Moffitt Cancer Center and Research Institute120 enrolled1 locationNCT07249775
Recruiting

Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma

Pancreas AdenocarcinomaCachexia
Wake Forest University Health Sciences100 enrolled2 locationsNCT05376592
Recruiting
Not Applicable

Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases

CancerCancer CachexiaInflammation+1 more
University of Erlangen-Nürnberg Medical School100 enrolled1 locationNCT04067167
Recruiting
Phase 1

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

Cachexia
AVEO Pharmaceuticals, Inc.30 enrolled12 locationsNCT05865535
Recruiting
Phase 1

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of SXRN Injection in Patients With Cancer Cachexia

Solid Tumor MalignanciesCachexia-Anorexia Syndrome
Jiangsu Nutai Biologics Co., Ltd54 enrolled1 locationNCT07231120
Recruiting

REVOLUTION Surgery (REVOLUTION Surgery)

Colorectal, CancerPancreatic CancerGastric Cancer+2 more
University of Edinburgh200 enrolled1 locationNCT05642819