Phase 2 Cancers Clinical Trials
65 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 65 trials
Recruiting
Phase 2Phase 3
Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE)
Gastric CancersColorectal, CancerPancreatic Ductal Adenocarcinoma+1 more
GE Healthcare175 enrolled2 locationsNCT07219238
Recruiting
Phase 2
Phase II Trial Comparison of 3 vs 4 Fractions (BRACHY-FIT).
Cervical Cancers
Stanford University41 enrolled1 locationNCT07022470
Recruiting
Phase 2
Using FAPI PET/MRI to Evaluate Prostate Cancer
Prostate CancersProstate Cancer Metastatic Disease
University of Wisconsin, Madison30 enrolled1 locationNCT06675357
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-8989 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutations
Non-small Cell Lung Cancer (NSCLC)Ovarian CancerEndometrial Cancer+4 more
Shenzhen Ionova Life Sciences Co., Ltd.178 enrolled1 locationNCT07610798
Recruiting
Phase 2
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Pancreatic Neuroendocrine TumorVon Hippel-Lindau DiseasePheochromocytoma/Paraganglioma+2 more
Merck Sharp & Dohme LLC355 enrolled84 locationsNCT04924075
Recruiting
Phase 2
Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer.
Gynecologic CancersEsophageal CancerGastrointestinal Cancers
John Waters50 enrolled1 locationNCT07039526
Recruiting
Phase 2
Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced Gastrointestinal (GI) Cancers
Gastrointestinal Cancers
Genmab160 enrolled2 locationsNCT07539311
Recruiting
Phase 2
A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies
Gynecologic CancersFallopian Tube CancerPlatinum-sensitive Ovarian Cancer+1 more
AbbVie377 enrolled16 locationsNCT07024784
Recruiting
Phase 2
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Breast CancerOvarian CancerNon-small Cell Lung Cancer+4 more
National Cancer Institute (NCI)285 enrolled1 locationNCT03412877
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-6452 in Adult Patients With Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Advanced/Metastatic Breast Cancer or Locally Advanced/Metastatic Solid Tumor
Ovarian CancerEndometrial CancerBreast Cancer (Locally Advanced or Metastatic)+2 more
Shenzhen Ionova Life Sciences Co., Ltd.201 enrolled1 locationNCT07612891
Recruiting
Phase 2
A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine
Primary Peritoneal CancerFallopian Tube CancersAdvanced High-Grade Epithelial Ovarian Cancer
AbbVie110 enrolled52 locationsNCT06682988
Recruiting
Phase 1Phase 2
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Advanced Liver Cancers
Hoffmann-La Roche518 enrolled33 locationsNCT04524871
Recruiting
Phase 1Phase 2
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
Gastric CancersColorectal, CancerPancreatic Cancer+1 more
Bold Therapeutics, Inc.220 enrolled24 locationsNCT04421820
Recruiting
Phase 1Phase 2
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Advanced Solid Cancers
BioNTech SE245 enrolled10 locationsNCT07186842
Recruiting
Phase 1Phase 2
AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Lung CancersUrothelial CancerLocally Advanced+5 more
Avenzo Therapeutics, Inc.480 enrolled18 locationsNCT07038343
Recruiting
Phase 2
Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gynecologic, Breast, or Lung Solid Tumors
Breast CancerGynecologic CancersOvarian Cancer+7 more
Peking University People's Hospital220 enrolled1 locationNCT07586826
Recruiting
Phase 1Phase 2
A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
Locally AdvancedUnresectableMetastatic Cancers+1 more
Recursion Pharmaceuticals Inc.170 enrolled6 locationsNCT06678659
Recruiting
Phase 1Phase 2
First-in-human Study of 7MW4911 in GI Cancer
GI Cancers
Mabwell (Shanghai) Bioscience Co., Ltd.200 enrolled5 locationsNCT07216560
Recruiting
Phase 2Phase 3
Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers
FatigueMetastatic Cancers
M.D. Anderson Cancer Center240 enrolled1 locationNCT06085716
Recruiting
Phase 2
Spatially Fractionated Radiotherapy Combined With Immunotherapy for Advanced Solid Tumors
Lung CancerRadiotherapyImmune Checkpoint Inhibitor+1 more
Tianjin Medical University Cancer Institute and Hospital30 enrolled3 locationsNCT07058948