Phase 2 Carcinoma In Situ Clinical Trials
17 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–17 of 17 trials
Recruiting
Phase 2
Evaluation of Novel Iron-based Lymphatic Mapping Agent, Magtrace, for Delayed Sentinel Lymph Node Biopsy (SLNB) in Ductal Carcinoma In-Situ (DCIS)
Ductal Carcinoma in Situ
University of Florida30 enrolled1 locationNCT06868238
Recruiting
Phase 2
A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)
Urinary Bladder NeoplasmsCarcinoma In SituNon-Muscle Invasive Bladder Neoplasms
Merck Sharp & Dohme LLC308 enrolled89 locationsNCT06833073
Recruiting
Phase 2
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
Breast CarcinomaBreast Ductal Carcinoma in SituBreast Atypical Hyperplasia+1 more
National Cancer Institute (NCI)66 enrolled3 locationsNCT06195306
Recruiting
Phase 2
DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment
Ductal Carcinoma in Situ
QuantumLeap Healthcare Collaborative400 enrolled28 locationsNCT06075953
Recruiting
Phase 2
Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
Breast CarcinomaBreast Ductal Carcinoma in SituBreast Atypical Hyperplasia+1 more
National Cancer Institute (NCI)80 enrolled4 locationsNCT05941520
Recruiting
Phase 2
Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
Breast CarcinomaEstrogen Receptor-Positive Breast CarcinomaBreast Ductal Carcinoma in Situ+3 more
National Cancer Institute (NCI)200 enrolled11 locationsNCT06184750
Recruiting
Phase 1Phase 2
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
Non-muscle Invasive Bladder Cancer With Carcinoma in SituSuperficial Bladder Cancer
enGene, Inc.350 enrolled101 locationsNCT04752722
Recruiting
Phase 2
High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
Estrogen Receptor-Positive Breast CarcinomaAnatomic Stage II Breast Cancer AJCC v8Anatomic Stage 0 Breast Cancer AJCC v8+5 more
City of Hope Medical Center36 enrolled1 locationNCT06538389
Recruiting
Phase 2
Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC
Urothelial CarcinomaBladder CancerNon-Muscle-Invasive Bladder Cancer (NMIBC)+8 more
Michael A. O'Donnell174 enrolled1 locationNCT07322263
Recruiting
Phase 2
Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)
Breast CancerDuctal Carcinoma in SituEarly Stage Breast Cancer+1 more
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT06902311
Recruiting
Phase 2
Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia
Cervical Intraepithelial NeoplasiaCervical Squamous Cell Carcinoma In SituCervical Squamous Intraepithelial Neoplasia 2
Jonsson Comprehensive Cancer Center25 enrolled1 locationNCT04712851
Recruiting
Phase 2
A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia
Oral Carcinoma in SituOropharyngeal DysplasiaOral Cavity Dysplasia
Elizabeth J Franzmann32 enrolled1 locationNCT05865028
Recruiting
Phase 2
5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer
Breast CancerDuctal Breast Carcinoma In SituInvasive Carcinoma of Breast
University of Utah144 enrolled1 locationNCT06961955
Recruiting
Phase 2Phase 3
5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
Superficial Basal Cell CarcinomaSquamous Cell Carcinoma in Situ
Boston University200 enrolled1 locationNCT05381597
Recruiting
Phase 2
Preoperative Partial Breast Irradiation in Early-Stage Breast Cancer
Breast CancerDuctal Carcinoma in SituInvasive Breast Cancer
Yonsei University47 enrolled1 locationNCT06677944
Recruiting
Phase 2
Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ
Ductal Carcinoma in SituExtensive DiseaseMastectomy
Institut Cancerologie de l'Ouest262 enrolled8 locationsNCT04666961
Completed
Phase 2
The EXCISE Study - EXcisional treatment Comparison for In Situ Endocervical adenocarinoma
Adenocarcinoma in situ (AIS) of the uterine cervix
St John of God Hospital, Subiaco WA 600840 enrolled6 locationsACTRN12617000132347