Carcinoma In Situ Clinical Trials

1 recruiting

Carcinoma In Situ Trials at a Glance

36 actively recruiting trials for carcinoma in situ are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Philadelphia, Los Angeles, and Nashville. Lead sponsors running carcinoma in situ studies include Thomas Jefferson University, University of Florida, and Boston University.

Browse carcinoma in situ trials by phase

Treatments under study

About Carcinoma In Situ Clinical Trials

Looking for clinical trials for Carcinoma In Situ? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Carcinoma In Situ trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Carcinoma In Situ clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 36 trials

Recruiting
Phase 1Phase 2

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Non-muscle Invasive Bladder Cancer With Carcinoma in SituSuperficial Bladder Cancer
enGene, Inc.350 enrolled101 locationsNCT04752722
Recruiting
Phase 2

Evaluation of Novel Iron-based Lymphatic Mapping Agent, Magtrace, for Delayed Sentinel Lymph Node Biopsy (SLNB) in Ductal Carcinoma In-Situ (DCIS)

Ductal Carcinoma in Situ
University of Florida30 enrolled1 locationNCT06868238
Recruiting
Phase 2

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

Ductal Carcinoma in Situ
QuantumLeap Healthcare Collaborative400 enrolled27 locationsNCT06075953
Recruiting
Phase 3

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Ferring Pharmaceuticals250 enrolled66 locationsNCT06545955
Recruiting

The PREDICT Registry:

DCISDuctal Breast Carcinoma In SituStage 0 Breast Cancer
PreludeDx3,000 enrolled30 locationsNCT03448926
Recruiting
Not Applicable

Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8+20 more
M.D. Anderson Cancer Center15 enrolled1 locationNCT02918474
Recruiting
Not Applicable

Endoscopic Nipple-Sparing Mastectomy Through a Single Axillary Incision in Breast Cancer

Breast CancerBreast Cancer - Ductal Carcinoma in Situ (DCIS)
Fondazione del Piemonte per l'Oncologia10 enrolled1 locationNCT07507890
Recruiting
Phase 1

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

Ductal Carcinoma in Situ
Finn, Olivera, PhD50 enrolled1 locationNCT06218303
Recruiting
Phase 2

Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia

Cervical Intraepithelial NeoplasiaCervical Squamous Cell Carcinoma In SituCervical Squamous Intraepithelial Neoplasia 2
Jonsson Comprehensive Cancer Center25 enrolled1 locationNCT04712851
Recruiting

Project: Every Child for Younger Patients With Cancer

Malignant Solid NeoplasmNeuroendocrine NeoplasmCentral Nervous System Neoplasm+15 more
Children's Oncology Group75,000 enrolled278 locationsNCT02402244
Recruiting
Not Applicable

A Patient Navigation Program for Addressing Disparities in Breast Cancer Care

Breast CarcinomaBreast Ductal Carcinoma in Situ
Roswell Park Cancer Institute126 enrolled1 locationNCT06350500
Recruiting
Not Applicable

EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

Breast CancerBreast Cancer FemaleBreast Carcinoma in Situ
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)30 enrolled1 locationNCT06115486
Recruiting

Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women

Breast CarcinomaBreast Atypical Ductal HyperplasiaBreast Atypical Lobular Hyperplasia+1 more
Mayo Clinic50 enrolled1 locationNCT05755269
Recruiting
Not Applicable

Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

Anatomic Stage 0 Breast Cancer AJCC v8Invasive Breast CarcinomaAnatomic Stage 1 Breast Cancer AJCC v8+3 more
Thomas Jefferson University80 enrolled1 locationNCT04959474
Recruiting

Validation of the Oncoliq Test for the Early Detection of Breast Cancer.

Breast Cancer FemaleBreast Cancer DetectionBreast Cancer Early Stage Breast Cancer (Stage 1-3)+4 more
Oncoliq US Inc300 enrolled1 locationNCT07331506
Recruiting
Phase 2

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Oral Carcinoma in SituOropharyngeal DysplasiaOral Cavity Dysplasia
Elizabeth J Franzmann32 enrolled1 locationNCT05865028
Recruiting
Phase 3

Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

Bladder Carcinoma in Situ (CIS)
Fidia Farmaceutici s.p.a.112 enrolled47 locationsNCT05024773
Recruiting
Not Applicable

Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions

Breast CancerDuctal Carcinoma in Situ
University of Florida50 enrolled1 locationNCT06903468
Recruiting
Phase 2Phase 3

5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer

Superficial Basal Cell CarcinomaSquamous Cell Carcinoma in Situ
Boston University200 enrolled1 locationNCT05381597
Recruiting

Prospective Breast Cancer Biospecimen Collection

Breast CancerInvasive Breast CancerCarcinoma in Situ of the Breast
Thomas Jefferson University200 enrolled1 locationNCT04074720