Early Phase 1 Carcinoma Clinical Trials
70 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 70 trials
Recruiting
Early Phase 1
Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer
Prostate CancerLocalized Prostate Carcinoma
Ivan de Kouchkovsky, MD80 enrolled1 locationNCT02526368
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
Safety and Feasibility of HIPEC for High-Risk Gallbladder Adenocarcinoma
Gallbladder Adenocarcinoma
West Virginia University10 enrolled1 locationNCT05430035
Recruiting
Early Phase 1
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
Cigarette Smoking-Related Carcinoma
Roswell Park Cancer Institute30 enrolled1 locationNCT06816459
Recruiting
Early Phase 1
Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Advanced Basal Cell Carcinoma
H. Lee Moffitt Cancer Center and Research Institute34 enrolled1 locationNCT05651828
Recruiting
Early Phase 1
Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma
Nasopharyngeal Carcinoma
Fudan University24 enrolled1 locationNCT05587543
Recruiting
Early Phase 1
Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma
Renal Cell Carcinoma
Abramson Cancer Center at Penn Medicine30 enrolled1 locationNCT05733715
Recruiting
Early Phase 1
OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1
Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center10 enrolled1 locationNCT04975217
Recruiting
Early Phase 1
Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer
Metastatic CancerCarcinomaAdenocarcinoma
Roberto Vargas4 enrolled1 locationNCT05065736
Recruiting
Early Phase 1
99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
Prostate CarcinomaRecurrent Prostate Carcinoma
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT04857502
Recruiting
Early Phase 1
Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial
Prostate Carcinoma
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT07164027
Recruiting
Early Phase 1
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Localized Prostate Carcinoma+1 more
Mayo Clinic220 enrolled2 locationsNCT05045066
Recruiting
Early Phase 1
Impact of Intraoperative ICG on Functional Outc in RARP
Prostate Adenocarcinoma
University of California, Irvine400 enrolled1 locationNCT06446648
Recruiting
Early Phase 1
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690
Recruiting
Early Phase 1
PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis
Peritoneal CarcinomatosisGastrointestinal Cancer
University of California, Irvine10 enrolled1 locationNCT06511037
Recruiting
Early Phase 1
Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma
Lung CancerLung AdenocarcinomaStage IA1 Lung Cancer American Joint Committee on Cancer (AJCC) v8+2 more
Jonsson Comprehensive Cancer Center48 enrolled1 locationNCT07235280
Recruiting
Early Phase 1
Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy
Recurrent Ovarian CarcinomaStage III Ovarian Cancer AJCC v8Stage IV Ovarian Cancer AJCC v8+2 more
Ohio State University Comprehensive Cancer Center161 enrolled1 locationNCT07144826
Recruiting
Early Phase 1
Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer
Stage IV Lung Cancer AJCC v8Stage IVA Lung Cancer AJCC v8Stage IVB Lung Cancer AJCC v8+1 more
Emory University15 enrolled1 locationNCT05493566
Recruiting
Early Phase 1
Intratumoral Injection of Standard Universal Donor Expanded Natural Killer Cells and TGF-beta Imprinted Natural Killer Cells for the Treatment of Skin Squamous Cell Carcinoma and Basal Cell Carcinoma
Skin Squamous Cell CarcinomaSkin Basal Cell CarcinomaSkin Nodular Basal Cell Carcinoma
Kirsten Johnson40 enrolled1 locationNCT07144384