Phase 4 Carcinoma Clinical Trials

35 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 35 trials

Recruiting
Phase 4

Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant

Hepatocellular Carcinoma
Icahn School of Medicine at Mount Sinai40 enrolled1 locationNCT07059494
Recruiting
Phase 4

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

CholangiocarcinomaSolid Tumor MalignanciesGlioma+1 more
Rigel Pharmaceuticals16 enrolled2 locationsNCT07486713
Recruiting
Phase 4

Studying the Relationship of Patient Positioning and Intravesical Bacillus Calmette Guerin Dwell Time to Improve the Treatment of Non-muscle Invasive Bladder Cancer

Non-Muscle Invasive Bladder Carcinoma
Ohio State University Comprehensive Cancer Center40 enrolled1 locationNCT07474519
Recruiting
Phase 4

A Safety Study of Enfortumab Vedotin in Indian Adults With Urothelial Cancer

Metastatic Urothelial Carcinoma
Astellas Pharma Global Development, Inc.100 enrolled10 locationsNCT06862219
Recruiting
Phase 4

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center10 enrolled1 locationNCT05376878
Recruiting
Phase 4

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more
Mayo Clinic75 enrolled1 locationNCT06764095
Recruiting
Phase 4

A Study of Revaree Plus in People With Breast Cancer

Breast CancerStage III Breast CancerStage I Breast Cancer+5 more
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07042581
Recruiting
Phase 4

Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8+2 more
University of Washington68 enrolled1 locationNCT05183828
Recruiting
Phase 4

Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)

Neuro Endocrine TumoursPDAC - Pancreatic Ductal AdenocarcinomaPancreas Adenocarcinoma+7 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)400 enrolled1 locationNCT07262957
Recruiting
Phase 4

Methylnatrexone In Resectable Head and Neck Squamous Cell Carcinoma (MINK). A "Window of Opportunity" Pilot Study.

Head and Neck Squamous Cell Carcinoma
M.D. Anderson Cancer Center25 enrolled1 locationNCT06162377
Recruiting
Phase 4

National Liver Cancer Screening Trial

Liver CancerCarcinoma, HepatocellularLiver Cirrhosis+1 more
University of Texas Southwestern Medical Center5,500 enrolled18 locationsNCT06084234
Recruiting
Phase 4

Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial

Cigarette Smoking-Related Carcinoma
M.D. Anderson Cancer Center2,010 enrolled1 locationNCT04604509
Recruiting
Phase 4

Digital Monitoring of Self-reported Symptoms by Patients Treated With Cabozantinib Plus Nivolumab for Advanced Clear-cell Renal Carcinoma

Metastatic Renal Cell CarcinomaLocally AdvancedRenal Cell Carcinoma (Kidney Cancer)
Centre Francois Baclesse83 enrolled10 locationsNCT07028125
Recruiting
Phase 4

Study of Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories

Bile Duct CarcinomaBile Duct Adenocarcinoma
University of Colorado, Denver75 enrolled1 locationNCT07120295
Recruiting
Phase 4

The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine

Hepatocellular Carcinoma (HCC)Liver Diseases
Anhui Provincial Hospital96 enrolled1 locationNCT07150624
Recruiting
Phase 4

Efficacy & Safety of Anticoagulants in Cirrhosis ± HCC

CirrhosisHCC - Hepatocellular CarcinomaPortal Vein Thrombosis
Mansoura University100 enrolled1 locationNCT07132515
Recruiting
Phase 4

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Esophageal AdenocarcinomaGastric AdenocarcinomaStage IIB Gastric Cancer+6 more
University of Chicago36 enrolled3 locationsNCT02366819
Recruiting
Phase 4

Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery

Colorectal CarcinomaAnalgesia, PostoperativeLaparotomy
Meri Mirceta98 enrolled1 locationNCT06935708
Recruiting
Phase 4

Treatment of Non-resectable Bile Duct Cancer with Radiofrequency Ablation or Photodynamic Therapy

Hilar Cholangiocarcinoma
University of Leipzig258 enrolled20 locationsNCT05551299
Recruiting
Phase 4

Endoscopic Variceal Ligation vs Carvedilol for the Prevention of First Esophageal Variceal Bleeding in Patients With HCC

Hepatocellular Carcinoma (HCC)Esophageal Varices
Taipei Veterans General Hospital, Taiwan120 enrolled1 locationNCT06594744