Cardiac Arrhythmia Clinical Trials

29 recruitingLast updated: June 18, 2026

There are 29 actively recruiting cardiac arrhythmia clinical trials across 19 countries. Studies span Not Applicable, Phase 3, Phase 4. Top locations include London, United Kingdom, Philadelphia, Pennsylvania, United States, La Jolla, California, United States. Updated daily from ClinicalTrials.gov.


Cardiac Arrhythmia Trials at a Glance

29 actively recruiting trials for cardiac arrhythmia are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in London, Philadelphia, and La Jolla. Lead sponsors running cardiac arrhythmia studies include Imperial College London, Pulse Biosciences, Inc., and Barts & The London NHS Trust.

Browse cardiac arrhythmia trials by phase

Treatments under study

About Cardiac Arrhythmia Clinical Trials

Looking for clinical trials for Cardiac Arrhythmia? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiac Arrhythmia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiac Arrhythmia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Phase 4

The Clinical Outcomes and Therapeutic Effects in Patients With Cardiac Implantable Electronic Device-detected Subclinical and Clinical Atrial Fibrillation.

Subclinical Atrial FibrillationCardiac Arrhythmias
National Taiwan University Hospital450 enrolled1 locationNCT07649109
Recruiting
Not Applicable

Cardiac Arrhythmia Telemetry; Conventional vs HeartWatch

Atrial Fibrillation (AF)Cardiac ArrhythmiaDiagnostic/Monitoring Devices Related to Adverse Incidents
HelpWear Inc.300 enrolled1 locationNCT06164808
Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Mantle Cell LymphomaSudden Cardiac DeathChronic Lymphocytic Leukemia (CLL)+3 more
National Heart, Lung, and Blood Institute (NHLBI)135 enrolled1 locationNCT05724121
Recruiting

ViewFlex X ICE First-in-Human Study

Cardiac Arrhythmias
Abbott Medical Devices500 enrolled8 locationsNCT06772493
Recruiting
Not Applicable

CellFX® Nanosecond Pulsed Field Ablation (PFA) 360 Catheter Ablation System for Treatment of Atrial Fibrillation

Atrial Fibrillation (Paroxysmal)Cardiac ArrhythmiaCardiac Ablation
Pulse Biosciences, Inc.60 enrolled3 locationsNCT06696170
Recruiting
Not Applicable

NS-PFA Catheter Ablation of Paroxysmal Atrial Fibrillation With the Pulse Biosciences CellFX System

Atrial Fibrillation (Paroxysmal)Cardiac ArrhythmiaCardiac Ablation
Pulse Biosciences, Inc.215 enrolled1 locationNCT07018596
Recruiting

Mayo AVC Registry and Biobank

CardiomyopathiesCardiovascular DiseasesSarcoidosis+14 more
Mayo Clinic1,000 enrolled2 locationsNCT03049254
Recruiting

AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)

CardiomyopathiesSudden Cardiac DeathCardiac Arrest+1 more
Idoven 1903 S.L.5,342 enrolled14 locationsNCT05890716
Recruiting
Not Applicable

StereoTactic Ablative RadioTherapy of Cardiac Arrhythmias

Cardiac Arrhythmia
University Health Network, Toronto60 enrolled1 locationNCT04843683
Recruiting
Not Applicable

Loop Recorder Implantation in Patients With Mitral Annular Disjunction

Arrhythmia, VentricularSudden Cardiac Death Due to Cardiac ArrhythmiaMitral Annular Disjunction+2 more
Gottsegen National Cardiovascular Institute20 enrolled1 locationNCT07436962
Recruiting
Not Applicable

Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest

Cardiac ArrestVentricular ArrythmiaVentricular Fibrillation+3 more
Queen Mary University of London40 enrolled1 locationNCT06071910
Recruiting

Post-market Clinical Follow-up Data Collection From Procedures With BIOTRONIK EP Products

Cardiac Arrhythmia
Biotronik SE & Co. KG280 enrolled1 locationNCT05560958
Recruiting
Not Applicable

Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)

Catheter AblationPersistent Atrial FibrillationCardiac Arrhythmia
Barts & The London NHS Trust208 enrolled1 locationNCT06096246
Recruiting

EluPro Antibiotic-Eluting BioEnvelope Registry

Cardiac Arrhythmias
Elutia Inc.100 enrolled4 locationsNCT06854081
Recruiting

Bad Berka Heart Rhythm Registry of Patients With or at Risk of Arrhythmias Treated at Heart Center Bad Berka

Cardiac Arrhythmias
Zentralklinik Bad Berka5,000 enrolled1 locationNCT07020910
Recruiting
Phase 3

Colchicine After Electrocardioversion for Atrial Fibrillation

Atrial FibrillationCardiac Arrhythmia
University Hospital, Basel, Switzerland416 enrolled8 locationsNCT05890664
Recruiting
Not Applicable

Smart Textile ECG Monitoring

Cardiac Arrhythmia
Myant Medical Corp.300 enrolled1 locationNCT06870175
Recruiting

Utility of Gene Test Analysis for Diagnosis, Prognosis and Treatment of Patients With Genetic Arrhythmic Heart Disease: the ARRHYTHMIC GENE-HEART

CardiologyGenetic DiseaseCardiac Disease+2 more
University Hospital of Ferrara200 enrolled1 locationNCT06898307
Recruiting

Tampere Coronary Artery Disease and Sudden Cardiac Arrest Study

Sudden Cardiac DeathCoronary Arterial Disease (CAD)Acute Coronary Event+2 more
Tampere Heart Hospital4,000 enrolled1 locationNCT06804499
Recruiting

French COhoRte Extra-Vascular Implantable CardiovErter DefibrillatoR

Defibrillators, ImplantableSudden Cardiac Death Due to Cardiac Arrhythmia
Paris Sudden Death Expertise Center1,000 enrolled1 locationNCT06739239