Early Phase 1 CED Clinical Trials
65 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 65 trials
Recruiting
Early Phase 1
NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors
Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Advanced Basal Cell Carcinoma
H. Lee Moffitt Cancer Center and Research Institute34 enrolled1 locationNCT05651828
Recruiting
Early Phase 1
Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors
Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1
OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1
Single Arm Romiplostim to Prevent CIT
Ewings SarcomaChemotherapy Induced Thrombocytopenia
Children's Hospital Medical Center, Cincinnati26 enrolled2 locationsNCT07048249
Recruiting
Early Phase 1
Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers
Advanced Solid Cancers
Hainan Cancer Hospital10 enrolled1 locationNCT07475182
Recruiting
Early Phase 1
Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+20 more
Ohio State University Comprehensive Cancer Center50 enrolled1 locationNCT05417308
Recruiting
Early Phase 1
A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX37 in Advanced/Metastatic Solid Tumors
NSCLCAdvanced/Metastatic Solid Tumors
Shanghai Henlius Biotech254 enrolled2 locationsNCT07274813
Recruiting
Early Phase 1
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690
Recruiting
Early Phase 1
Respiratory and Real-time Dynamics in Exercise-Induced Paradoxical Vocal Fold Motion
Vocal Cord DysfunctionExercise-Induced Vocal Cord DysfunctionParadoxical Vocal Fold Motion
Indiana University120 enrolled1 locationNCT07420530
Recruiting
Early Phase 1
Exploratory Clinical Study of cCTL in Combination With Immunotherapy for Advanced Gynecologic Malignancies
Advanced Gynecological Cancers
Obstetrics & Gynecology Hospital of Fudan University20 enrolled1 locationNCT07434284
Recruiting
Early Phase 1
Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy
Recurrent Ovarian CarcinomaStage III Ovarian Cancer AJCC v8Stage IV Ovarian Cancer AJCC v8+2 more
Ohio State University Comprehensive Cancer Center161 enrolled1 locationNCT07144826
Recruiting
Early Phase 1
A Single-Arm, Open-Label Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.
Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD10 enrolled1 locationNCT07414316
Recruiting
Early Phase 1
Exploratory Clinical Study of Claudin18.2-Targeted Activated DC and CAR-T Therapy in Advanced Pancreatic Cancer.
Advanced Pancreatic Cancer
Hainan Cancer Hospital10 enrolled1 locationNCT07416240
Recruiting
Early Phase 1
HEAT Trial (HER2 Antibody Therapy With Lutetium-177)
Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1
Ketones, SGLT2, HFrEF
Heart Failure With Reduced Ejection FractionType2diabetes
The University of Texas Health Science Center at San Antonio71 enrolled1 locationNCT06229678
Recruiting
Early Phase 1
A Platform Study of In Vivo CAR-T for Treating Advanced Malignant Tumors Based on Target Screening
Advanced Malignant Tumours
Cancer Institute and Hospital, Chinese Academy of Medical Sciences50 enrolled1 locationNCT07395479
Recruiting
Early Phase 1
A Clinical Study of GK02 in Malignant Ascites
Malignant Ascites Caused by Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD9 enrolled1 locationNCT07378436
Recruiting
Early Phase 1
Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
Type 2 DiabetesHeart Failure, Reduced Ejection Fraction
The University of Texas Health Science Center at San Antonio10 enrolled1 locationNCT06108076