RecruitingNCT06054295

Somatic Mosaicism in Twins Discordant for Childhood Cancer

Somatic Mosaicism in Twins Discordant for Childhood Cancer: a Pilot Study

Sponsor

Children's Oncology Group

Enrollment

50 participants

Start Date

Jun 3, 2024

Study Type

OBSERVATIONAL

Conditions

Central Nervous System Tumor Somatic Mutation Pediatric Central Nervous System Tumor Discordant Twin

Summary

Somatic mosaicism in cancer associated genes is one potential explanation for discordance in childhood cancer that has not been fully explored to date. This pilot study will focus on twins with central nervous system (CNS) tumors who are identified through the Children's Oncology Group's Project: EveryChild (PEC) registry or volunteer.

Eligibility

Max Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Biospecimen collection and Questionnaire Administration for people with central nervous system tumor, discordant twin, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include up to age 18 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBiospecimen collection

Collection of both blood and saliva samples from participants at the time of study enrollment

OTHERQuestionnaire Administration

The brief questionnaire will assess health history, demographics, environmental exposures, family history of cancer, and birth characteristics.

Locations(1)

University of Minnesota

Minneapolis, Minnesota, United States

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NCT06054295

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