Phase 2 Child Clinical Trials
69 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 69 trials
Recruiting
Phase 2
Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure
Unresectable or Metastatic Hepatocellular CarcinomaChild-Pugh A Hepatocellular CarcinomaFailure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
CatalYm GmbH104 enrolled2 locationsNCT07219459
Recruiting
Phase 1Phase 2
Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors
GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard70 enrolled11 locationsNCT07243470
Recruiting
Phase 2
Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults
CraniopharyngiomaCraniopharyngioma, ChildRecurrent Craniopharyngioma
Sabine Mueller, MD, PhD57 enrolled20 locationsNCT05465174
Recruiting
Phase 1Phase 2
Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders
Childhood-onset Systemic Lupus Erythematous
Cartesian Therapeutics50 enrolled2 locationsNCT07089121
Recruiting
Phase 1Phase 2
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 2
To Investigate the Effects of Bifidobacterium Animalis Subsp. Lactis XLTG11 on Growth and Development, Incidence of Allergy and Immune Function in Infants
Healthy Children
Min-Tze LIONG366 enrolled2 locationsNCT07490587
Recruiting
Phase 2
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
NeoplasmsAdolescentChild
Eli Lilly and Company105 enrolled73 locationsNCT05999994
Recruiting
Phase 2Phase 3
Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment
TreatmentSurvivalClassical Hodgkin Lymphoma+6 more
Children's Cancer Group, China96 enrolled1 locationNCT06563245
Recruiting
Phase 1Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled31 locationsNCT06783309
Recruiting
Phase 2
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
Pain, PostoperativeAnalgesiaMedial Patellofemoral Ligament (MPFL) Reconstruction+1 more
Texas Scottish Rite Hospital for Children100 enrolled1 locationNCT06559215
Recruiting
Phase 2
A Clinical Trial of Soluble Fiber for Asthma
Asthma in Children
Phoenix Children's Hospital105 enrolled1 locationNCT06372249
Recruiting
Phase 2
A Study of Anti-CD38 Monoclonal Antibody (SG301) Subcutaneous Injection in Children With Nephrotic Syndrome With Frequent Relapses or Steroid Dependence
Nephrotic Syndrome in Children
Mao Jianhua30 enrolled1 locationNCT07087314
Recruiting
Phase 1Phase 2
Tolerance Results and Immune Mechanisms in Cow´s Milk and/or Hen´s Egg Allergic Children Following Natural Evolution or Oral Immunotherapy
Food Allergy in Children
Fundación de Investigación Biomédica - Hospital Universitario de La Princesa68 enrolled1 locationNCT07419243
Recruiting
Phase 2
Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma
Liver CancerFibrolamellar CarcinomaHepatocellular Carcinoma, Childhood+1 more
Allison O'Neill, MD18 enrolled5 locationsNCT04134559
Recruiting
Phase 1Phase 2
Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRefractory Childhood Malignant Solid Neoplasm+6 more
Children's Oncology Group81 enrolled20 locationsNCT06620302
Recruiting
Phase 2Phase 3
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study
Food Allergy in ChildrenMilk Allergy
Pablo Rodríguez del Rio40 enrolled1 locationNCT06976775
Recruiting
Phase 2
A Phase II Study of PEG-rhGH Injection for Short Children Born Small for Gestational Age: Efficacy, Safety, and Pharmacokinetics
Short Stature Children Born Small for Gestational Age (SGA)
Changchun GeneScience Pharmaceutical Co., Ltd.72 enrolled1 locationNCT07260500
Recruiting
Phase 2
A Study to Give Treatment Inside the Eye to Treat Retinoblastoma
Unilateral RetinoblastomaBilateral RetinoblastomaChildhood Intraocular Retinoblastoma+2 more
Children's Oncology Group26 enrolled20 locationsNCT05504291
Recruiting
Phase 2
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia
Refractory Acute Lymphoblastic LeukemiaRecurrent Acute Lymphoblastic LeukemiaRecurrent Adult Lymphoblastic Lymphoma+8 more
M.D. Anderson Cancer Center42 enrolled1 locationNCT03136146
Recruiting
Phase 1Phase 2
Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML
AML, Childhood
Washington University School of Medicine68 enrolled1 locationNCT06158828