Phase 2 Child Clinical Trials

81 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 81 trials

Recruiting
Phase 2

Phentermine's Impact on Treatment in Teens

Childhood Obesity
Russell McCulloh, MD240 enrolled2 locationsNCT07282340
Recruiting
Phase 1Phase 2

CANnabinoids in Pediatric ONCology

CancerChildhood Cancer
University of Manitoba60 enrolled3 locationsNCT05754840
Recruiting
Phase 2

Phase II Study of Chidamide-Dinutuximab Beta-Irinotecan-Temozolomide for Refractory/Relapsed Neuroblastoma in Children

Neuroblastoma (NB)Neuroblastoma in Children
Tianjin Medical University Cancer Institute and Hospital27 enrolled1 locationNCT07318831
Recruiting
Phase 1Phase 2

Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors

GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard70 enrolled12 locationsNCT07243470
Recruiting
Phase 1Phase 2

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled30 locationsNCT06783309
Recruiting
Phase 2

Substance Misuse and Family Violence Treatment Fathers

Child abuseSubstance MisuseViolence, Domestic
Yale University280 enrolled2 locationsNCT06650267
Recruiting
Phase 2

Doxorubicin Hydrochloride Liposome Combined With Irinotecan (AI Regimen) Versus VIT Regimen in the Treatment of Relapsed and Refractory Pediatric Rhabdomyosarcoma: a Prospective, Open-label, Randomized Controlled, Multicenter, Phase II Clinical Study

Rhabdomyosarcoma, Child
Sun Yat-sen University88 enrolled1 locationNCT05457829
Recruiting
Phase 2

Vasodilator and Exercise Study for DMD (VASO-REx)

ExerciseDuchenne Muscular DystrophyDMD+4 more
University of Florida50 enrolled1 locationNCT06290713
Recruiting
Phase 2

Boiled Tree Nut for Oral Immunotherapy in Food-allergic Children

Food allergyFood Allergy in Children
Chinese University of Hong Kong75 enrolled1 locationNCT06467994
Recruiting
Phase 2

Telpegfilgrastim vs Filgrastim for Secondary Prevention of Chemotherapy-Induced Neutropenia in Pediatric Solid Tumors

Solid TumorsChemotherapy-induced NeutropeniaAdolescent+1 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences132 enrolled1 locationNCT06926751
Recruiting
Phase 2

A Prospective, Single-arm Clinical Study of Liposomal Mitoxantrone Combination Regimen in the Treatment of Relapsed and Refractory Solid Tumors in Children, Adolescents and Young Adults

Solid TumorsAdolescentsChildren
Cancer Institute and Hospital, Chinese Academy of Medical Sciences49 enrolled1 locationNCT06761417
Recruiting
Phase 2

Romiplostim N01 for Chemotherapy-Induced Thrombocytopenia in Pediatric Cancer Patients

Solid TumorsAdolescentChemotherapy Induced Thrombocytopenia+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences50 enrolled1 locationNCT07043894
Recruiting
Phase 1Phase 2

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRefractory Childhood Malignant Solid Neoplasm+6 more
Children's Oncology Group81 enrolled21 locationsNCT06620302
Recruiting
Phase 1Phase 2

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

Acute Myeloid LeukemiaAMLAML, Childhood+1 more
Washington University School of Medicine68 enrolled1 locationNCT06158828
Recruiting
Phase 2

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

Unresectable or Metastatic Hepatocellular CarcinomaChild-Pugh A Hepatocellular CarcinomaFailure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
CatalYm GmbH104 enrolled2 locationsNCT07219459
Recruiting
Phase 2

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

CraniopharyngiomaCraniopharyngioma, ChildRecurrent Craniopharyngioma
Sabine Mueller, MD, PhD57 enrolled20 locationsNCT05465174
Recruiting
Phase 2

Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy

Obesity in childrenObesityLifestyle Modification+3 more
University of Virginia120 enrolled1 locationNCT06903923
Recruiting
Phase 1Phase 2

Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders

Juvenile Myasthenia GravisANCA Associated Vasculitis (AAV)Juvenile Dermatomyositis+1 more
Cartesian Therapeutics50 enrolled2 locationsNCT07089121
Recruiting
Phase 1Phase 2

Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children

Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 2

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

NeoplasmsAdolescentChild
Eli Lilly and Company105 enrolled73 locationsNCT05999994