Phase 3 Child Clinical Trials

75 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 75 trials

Recruiting
Phase 3

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

Cognitive ImpairmentMedulloblastoma, Childhood
Donald Mabbott140 enrolled20 locationsNCT05230758
Recruiting
Phase 3

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuriaChildren
Bayer100 enrolled178 locationsNCT05457283
Recruiting
Phase 3

A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

Childhood Absence EpilepsyJuvenile Absence Epilepsy
UCB Biopharma SRL120 enrolled23 locationsNCT06315322
Recruiting
Phase 3

Multi-center Trial of Ferric Derisomaltose in Children 0 to <18 Years of Age With Iron Deficiency Anemia

Iron Deficiency, Anaemia in Children
Pharmacosmos A/S200 enrolled1 locationNCT05179226
Recruiting
Phase 3

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Germ Cell TumorChildhood Extracranial Germ Cell TumorExtragonadal Embryonal Carcinoma+27 more
Children's Oncology Group1,780 enrolled630 locationsNCT03067181
Recruiting
Phase 3

Oraverse Versus Laser

Reversal of Local Anesthesia in Children
sara nabil36 enrolled1 locationNCT05473858
Recruiting
Phase 3

An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors

Malignant Abdominal NeoplasmChildhood Malignant Solid NeoplasmChildhood Malignant Thoracic Neoplasm+3 more
Mayo Clinic20 enrolled1 locationNCT06915727
Recruiting
Phase 2Phase 3

Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment

TreatmentSurvivalClassical Hodgkin Lymphoma+6 more
Children's Cancer Group, China96 enrolled1 locationNCT06563245
Recruiting
Phase 3

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

Chronic Migraine in Children
H. Lundbeck A/S285 enrolled84 locationsNCT04965675
Recruiting
Phase 3

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Childhood Medulloblastoma
Children's Oncology Group225 enrolled103 locationsNCT05382338
Recruiting
Phase 2Phase 3

Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study

Food Allergy in ChildrenMilk Allergy
Pablo Rodríguez del Rio40 enrolled1 locationNCT06976775
Recruiting
Phase 3

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546
Recruiting
Phase 3

Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents

Intensive Care Units, PediatricAnesthetics, InhalationMechanically Ventilated, Critically Ill Children
Sunnybrook Health Sciences Centre60 enrolled3 locationsNCT05867472
Recruiting
Phase 3

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

Mental Health IssueParent-Child Relations
Yale University124 enrolled2 locationsNCT05766592
Recruiting
Phase 3

Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)

Urinary Incontinence in Children
University of Aarhus236 enrolled5 locationsNCT06551246
Recruiting
Phase 3

Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance

Insulin ResistanceObesity, Childhood
University of Alberta90 enrolled1 locationNCT04578652
Recruiting
Phase 2Phase 3

Inhaled Isopropyl Alcohol for Treatment of Nausea

VomitingChildren, OnlyNausea
State University of New York at Buffalo84 enrolled1 locationNCT05418244
Recruiting
Phase 3

VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma

AsthmaFractures, BoneAllergy+8 more
Professor Klaus Bønnelykke2,000 enrolled1 locationNCT06570889
Recruiting
Phase 3

Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma

AsthmaFractures, BoneAllergy+8 more
Professor Klaus Bønnelykke2,000 enrolled1 locationNCT06560255
Recruiting
Phase 2Phase 3

Food-Body-Mind Intervention (16 Weeks)

Obesity, ChildhoodMental Health WellnessSocial Skills+2 more
Michigan State University800 enrolled1 locationNCT06597474