Phase 3 Cholesterolemia Clinical Trials

10 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 110 of 10 trials

Recruiting
Phase 3

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals195 enrolled52 locationsNCT05682378
Recruiting
Phase 2Phase 3

A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC153 enrolled24 locationsNCT07058077
Recruiting
Phase 3

A Study to Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia

Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.760 enrolled2 locationsNCT07421297
Recruiting
Phase 3

A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals60 enrolled22 locationsNCT07037771
Recruiting
Phase 3

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals9 enrolled18 locationsNCT06597006
Recruiting
Phase 3

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals51 enrolled66 locationsNCT06597019
Recruiting
Phase 3

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

DyslipidemiasHypercholesterolemia
Hasten Biopharmaceutical Co., Ltd.210 enrolled18 locationsNCT06568471
Recruiting
Phase 2Phase 3

Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women

DyslipidemiasPostmenopausal SymptomsHypercholesterolemia+3 more
Dhurakij Pundit University10 enrolled1 locationNCT06220266
Completed
Phase 2Phase 3

Dose response study of phytosterols in tablet dosage in adults with primary hypercholeterolemia

Primary hypercholesterolemia
Mayne Health Consumer Products80 enrolled1 locationACTRN12605000303640
Completed
Phase 3

Study on the Safety and Efficacy of Sylvan Red Yeast Rice in Adults with Primary Hypercholesterolemia

Hypercholesterolemia
Sylvan Australia Pty Ltd72 enrolled1 locationACTRN12605000288628