Chondrosarcoma Clinical Trials

14 recruiting

Chondrosarcoma Trials at a Glance

18 actively recruiting trials for chondrosarcoma are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Phase 2 with 5 trials, with the heaviest enrollment activity in Jacksonville, Columbus, and Bologna. Lead sponsors running chondrosarcoma studies include Centre Leon Berard, EpicentRx, Inc., and Centre Antoine Lacassagne.

Browse chondrosarcoma trials by phase

Treatments under study

About Chondrosarcoma Clinical Trials

Looking for clinical trials for Chondrosarcoma? There are currently 14 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chondrosarcoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chondrosarcoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 118 of 18 trials

Recruiting
Phase 2

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Metastatic ChondrosarcomaLocally Advanced ChondrosarcomaMetastatic Sinonasal Adenocarcinoma+7 more
National Cancer Institute (NCI)40 enrolled1 locationNCT06176989
Recruiting

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

OsteosarcomaChondrosarcomaBone Sarcoma+3 more
Memorial Sloan Kettering Cancer Center300 enrolled5 locationsNCT03442465
Recruiting
Phase 1

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Stage IIIA Uterine Corpus Cancer AJCC v8+35 more
M.D. Anderson Cancer Center54 enrolled1 locationNCT05039801
Recruiting
Phase 2

Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma

Mesenchymal Chondrosarcoma
Italian Sarcoma Group16 enrolled7 locationsNCT04305548
Recruiting

Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone

ChondrosarcomaBone SarcomaChordoma+2 more
Mayo Clinic72 enrolled3 locationsNCT05033288
Recruiting
Not Applicable

Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

AngiosarcomaOsteosarcomaEwing Sarcoma+4 more
Centre Leon Berard168 enrolled16 locationsNCT04055220
Recruiting
Phase 3

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Servier Bio-Innovation LLC136 enrolled114 locationsNCT06127407
Recruiting
Not Applicable

A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning

OsteosarcomaChondrosarcomaSarcoma, Ewing+2 more
Ricoh USA, Inc.150 enrolled3 locationsNCT06387485
Recruiting

Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery

OsteosarcomaEwing SarcomaChondrosarcoma+1 more
Istituto Ortopedico Rizzoli50 enrolled1 locationNCT05779670
Recruiting
Not Applicable

Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base

ChondrosarcomaChordoma
Quironsalud20 enrolled1 locationNCT05861245
Recruiting

Diagnostic and Therapeutic Targets in Cartilaginous Tumours

ChondrosarcomasCartilage Tumours
St. Anne's University Hospital Brno, Czech Republic300 enrolled1 locationNCT07315542
Recruiting
Early Phase 1

PET-imaging of Two Vartumabs in Patients With Solid Tumors

Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Phase 2

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Soft Tissue SarcomaOsteosarcomaChondrosarcoma
Medical College of Wisconsin44 enrolled4 locationsNCT04040205
Recruiting

Long-Term Longitudinal QoL in Patients Undergoing EEA

ChondrosarcomaMeningiomaPituitary Tumor+5 more
Ohio State University400 enrolled1 locationNCT04087902
Recruiting
Phase 2

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

SarcomaCancerSolid Tumor, Adult+3 more
EpicentRx, Inc.140 enrolled6 locationsNCT04673942
Recruiting
Not Applicable

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy

OsteosarcomaEwing SarcomaChondrosarcoma+1 more
Centre Antoine Lacassagne106 enrolled1 locationNCT06029218
Recruiting

Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas

ChondrosarcomaMagnetic Resonance ImagingChordoma+1 more
Leiden University Medical Center40 enrolled2 locationsNCT04832620
Recruiting
Phase 2

A Study of Anlotinib Combined With or Without PD-1 Antibody on Unresectable High-grade Chondrosarcoma

Chondrosarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University70 enrolled1 locationNCT05193188