chronic cough Clinical Trials

3 recruiting

chronic cough Trials at a Glance

11 actively recruiting trials for chronic cough are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Early Phase 1 with 2 trials, with the heaviest enrollment activity in Hamilton, Québec, and Missoula. Lead sponsors running chronic cough studies include McMaster University, Mayo Clinic, and Hyfe Inc.

Browse chronic cough trials by phase

Treatments under study

About chronic cough Clinical Trials

Looking for clinical trials for chronic cough? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new chronic cough trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about chronic cough clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 2

Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough

Refractory or Unexplained Chronic Cough
Nocion Therapeutics455 enrolled107 locationsNCT06504446
Recruiting
Phase 2

Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough

Refractory Chronic Cough
Mayo Clinic50 enrolled1 locationNCT05110144
Recruiting

Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough

AsthmaChronic Obstructive Pulmonary Disease (COPD)Chronic Cough (CC)
McMaster University240 enrolled6 locationsNCT06858748
Recruiting
Phase 3

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Refractory Chronic CoughCough
Bellus Health Inc. - a GSK company975 enrolled242 locationsNCT05600777
Recruiting
Not Applicable

Cough Management Wellness App for Refractory or Unexplained Chronic Cough

Refractory Chronic CoughUnexplained Chronic CoughCough Hypersensitivity
Hyfe Inc20 enrolled1 locationNCT07070895
Recruiting
Phase 1

The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges

AsthmaChronic Cough (CC)
McMaster University33 enrolled1 locationNCT07085975
Recruiting
Early Phase 1

Efficacy of Intramuscular Steroid Injection for Chronic Cough.

CoughingLaryngeal DiseaseChronic Cough (CC)
Medical University of South Carolina40 enrolled1 locationNCT06634823
Recruiting

Investigating the Role of ATP Production by Airway Epithelium in Patients With Refractory and Unexplained Chronic Cough (RCC/UCC).

Chronic Cough (CC)
McMaster University30 enrolled1 locationNCT06600646
Recruiting

Impact of Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise

Chronic Cough (CC)
University of Leeds129 enrolled1 locationNCT06766175
Recruiting
Early Phase 1

Group Telehealth Behavioral Cough Suppression Therapy

Refractory Chronic Cough
University of Montana60 enrolled1 locationNCT06706765
Recruiting
Phase 4

Randomised placebo controlled trial of inhaled corticosteroids for treatment of chronic cough in children.

Chronic cough in children.
Prof Anne Chang77 enrolled2 locationsACTRN12616001713482