chronic cough Clinical Trials

17 recruitingLast updated: June 18, 2026

There are 17 actively recruiting chronic cough clinical trials across 17 countries. Studies span Early Phase 1, Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4. Top locations include Hamilton, Ontario, Canada, Québec, Quebec, Canada, Missoula, Montana, United States. Updated daily from ClinicalTrials.gov.


chronic cough Trials at a Glance

17 actively recruiting trials for chronic cough are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Early Phase 1 with 3 trials, with the heaviest enrollment activity in Hamilton, Québec, and Missoula. Lead sponsors running chronic cough studies include McMaster University, Hull University Teaching Hospitals NHS Trust, and Bellus Health Inc. - a GSK company.

Browse chronic cough trials by phase

Treatments under study

About chronic cough Clinical Trials

Looking for clinical trials for chronic cough? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new chronic cough trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about chronic cough clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Phase 3

Finnish Children´s Protracted Cough

chronic cough
Tampere University Hospital100 enrolled1 locationNCT07582549
Recruiting
Not Applicable

Efficacy of Behavioral Therapy for Chronic Refractory Cough

chronic cough
Assiut University30 enrolled1 locationNCT07488598
Recruiting
Phase 2

Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough

Refractory or Unexplained Chronic Cough
Nocion Therapeutics455 enrolled107 locationsNCT06504446
Recruiting
Phase 2

Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough

Refractory Chronic Cough
Mayo Clinic50 enrolled1 locationNCT05110144
Recruiting

Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough

AsthmaChronic Obstructive Pulmonary Disease (COPD)Chronic Cough (CC)
McMaster University240 enrolled6 locationsNCT06858748
Recruiting
Phase 3

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Refractory Chronic CoughCough
Bellus Health Inc. - a GSK company975 enrolled242 locationsNCT05600777
Recruiting
Not Applicable

Cough Management Wellness App for Refractory or Unexplained Chronic Cough

Refractory Chronic CoughUnexplained Chronic CoughCough Hypersensitivity
Hyfe Inc20 enrolled1 locationNCT07070895
Recruiting
Phase 1

The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges

AsthmaChronic Cough (CC)
McMaster University33 enrolled1 locationNCT07085975
Recruiting

An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough

chronic cough
Hull University Teaching Hospitals NHS Trust60 enrolled1 locationNCT06376448
Recruiting
Early Phase 1

Efficacy of Intramuscular Steroid Injection for Chronic Cough.

CoughingLaryngeal DiseaseChronic Cough (CC)
Medical University of South Carolina40 enrolled1 locationNCT06634823
Recruiting

Investigating the Role of ATP Production by Airway Epithelium in Patients With Refractory and Unexplained Chronic Cough (RCC/UCC).

Chronic Cough (CC)
McMaster University30 enrolled1 locationNCT06600646
Recruiting

Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients

chronic cough
Imperial College London18 enrolled2 locationsNCT06286163
Recruiting
Not Applicable

The Real-world Treatment Satisfaction by Gefapixiant in RCC

chronic cough
Nagoya City University63 enrolled2 locationsNCT06542484
Recruiting

Impact of Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise

Chronic Cough (CC)
University of Leeds129 enrolled1 locationNCT06766175
Recruiting
Early Phase 1

Group Telehealth Behavioral Cough Suppression Therapy

Refractory Chronic Cough
University of Montana60 enrolled1 locationNCT06706765
Recruiting
Early Phase 1

Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough

chronic cough
Stuart Mazzone31 enrolled1 locationNCT05813223
Recruiting
Phase 4

Randomised placebo controlled trial of inhaled corticosteroids for treatment of chronic cough in children.

Chronic cough in children.
Prof Anne Chang77 enrolled2 locationsACTRN12616001713482