Chronic Musculoskeletal Pain Clinical Trials

12 recruiting

Chronic Musculoskeletal Pain Trials at a Glance

11 actively recruiting trials for chronic musculoskeletal pain are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in Boston, Chicago, and Detroit. Lead sponsors running chronic musculoskeletal pain studies include University of Thessaly, VA Office of Research and Development, and Henry M. Jackson Foundation for the Advancement of Military Medicine.

Browse chronic musculoskeletal pain trials by phase

Treatments under study

About Chronic Musculoskeletal Pain Clinical Trials

Looking for clinical trials for Chronic Musculoskeletal Pain? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic Musculoskeletal Pain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic Musculoskeletal Pain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Pain Disengagement Training (Open Pilot)

Chronic Musculoskeletal Pain
Massachusetts General Hospital10 enrolled1 locationNCT06870162
Recruiting
Not Applicable

Neural Mobilization to Improve Chronic Musculoskeletal Pain in Older Adults

Chronic Musculoskeletal Pain
Aveiro University4 enrolled1 locationNCT07449819
Recruiting
Not Applicable

The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain

COPDChronic Musculoskeletal Pain
VA Office of Research and Development136 enrolled1 locationNCT05701982
Recruiting
Not Applicable

Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial

VeteransChronic Musculoskeletal PainMusic Therapy
Henry M. Jackson Foundation for the Advancement of Military Medicine180 enrolled1 locationNCT07217821
Recruiting
Not Applicable

This Project is a Three-arm RCT Evaluating Two, Single-session Behavioral Interventions for Adults With Chronic Musculoskeletal Pain (CMP) -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE) vs. Empowered Relief (ER) -- Relative to the Traditional 8-week Version of MORE.

Chronic Musculoskeletal Pain
Florida State University39 enrolled1 locationNCT07193095
Recruiting
Not Applicable

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

Chronic Musculoskeletal Pain
VA Office of Research and Development216 enrolled2 locationsNCT06004804
Recruiting
Not Applicable

Culturally Adapted EAET-H for Chronic Pain Patients Using Medical Cannabis in Israel - A Pilot Study

Cannabis UseChronic Musculoskeletal Pain
Reuth Rehabilitation Hospital8 enrolled1 locationNCT07168707
Recruiting
Not Applicable

Comparing Single-Session Therapies for Chronic Pain

Chronic Musculoskeletal Pain
Mark A. Lumley160 enrolled2 locationsNCT07008105
Recruiting
Not Applicable

Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain

Chronic Musculoskeletal Pain
University of Thessaly90 enrolled1 locationNCT07001449
Recruiting
Not Applicable

Community-based Exercise for Older Adults With Chronic Musculoskeletal Pain

Chronic Musculoskeletal Pain
University of Limerick72 enrolled1 locationNCT06535633
Recruiting
Not Applicable

Effectiveness of Physiotherapist's Communication Skills on Clinical Outcomes in Chronic Musculoskeletal Patients

Chronic Musculoskeletal Pain
University of Thessaly69 enrolled1 locationNCT06175884