Shoulder Osteoarthritis Clinical Trials

17 recruitingLast updated: May 21, 2026

There are 17 actively recruiting shoulder osteoarthritis clinical trials across 10 countries. Studies span Not Applicable, Phase 4, Phase 1, Phase 2. Top locations include Philadelphia, Pennsylvania, United States, Bloomington, Minnesota, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Shoulder Osteoarthritis Trials at a Glance

17 actively recruiting trials for shoulder osteoarthritis are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Philadelphia, Bloomington, and New York. Lead sponsors running shoulder osteoarthritis studies include Hospital for Special Surgery, New York, Lovisenberg Diakonale Hospital, and Deakin University.

Browse shoulder osteoarthritis trials by phase

About Shoulder Osteoarthritis Clinical Trials

Looking for clinical trials for Shoulder Osteoarthritis? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Shoulder Osteoarthritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Shoulder Osteoarthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Not Applicable

Zimmer Biomet Shoulder Arthroplasty PMCF

Shoulder PainShoulder OsteoarthritisShoulder Injuries+3 more
Zimmer Biomet584 enrolled17 locationsNCT04984291
Recruiting
Phase 1Phase 2

CBD for Pain Following Orthopedic Shoulder Surgery

Shoulder Osteoarthritisrotator cuff injuries
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting

Return to Golf After Orthopaedic Surgery

Knee OsteoarthritisShoulder Osteoarthritiship osteoarthritis
Hospital for Special Surgery, New York432 enrolled2 locationsNCT05675618
Recruiting
Not Applicable

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Shoulder Osteoarthritis(OA)

myofascial trigger pointsShoulder OsteoarthritisChronic Musculoskeletal Pain
Beijing Tiantan Hospital1,036 enrolled1 locationNCT07347054
Recruiting
Phase 4

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

Post Operative PainAnesthesiaNerve Block+1 more
Melinda Seering56 enrolled1 locationNCT05868330
Recruiting
Phase 4

PRP for Glenohumeral Osteoarthritis

Shoulder Osteoarthritis
Hospital for Special Surgery, New York135 enrolled1 locationNCT05675527
Recruiting
Not Applicable

Rehabilitation Following Reverse Total Shoulder Arthroplasty

Shoulder Osteoarthritis
HealthPartners Institute74 enrolled1 locationNCT03804853
Recruiting
Not Applicable

Clinical Evaluation of Reverse Versus Anatomic Shoulder Arthroplasty Techniques in the Treatment of Osteoarthritis

Shoulder Osteoarthritis
University of Alberta40 enrolled8 locationsNCT05395819
Recruiting
Not Applicable

Could a Feedback Device Help Manage Work-related Shoulder Disorders?

Rheumatoid Arthritis (RA)Rotator Cuff-related Shoulder PainShoulder Osteoarthritis
Laval University42 enrolled1 locationNCT06693479
Recruiting
Not Applicable

Scapular Positioning in Standing Position Using Sonography

Shoulder OsteoarthritisArthropathy Shoulder
University Hospital, Brest30 enrolled1 locationNCT04449146
Recruiting

AETOS Shoulder System

Shoulder OsteoarthritisShoulder Arthritis
Smith & Nephew, Inc.220 enrolled5 locationsNCT06319911
Recruiting
Not Applicable

Comparison of the Analgesic Effect of 2 Shoulder Infiltrations

Shoulder OsteoarthritisInfiltration
Centre hospitalier de l'Université de Montréal (CHUM)84 enrolled1 locationNCT05408065
Recruiting
Not Applicable

Does BIO-RSA Provides Superior Clinical Outcome Compared to Conventional RSA?

Shoulder OsteoarthritisArthroplasty, Replacement, Shoulder
Lovisenberg Diakonale Hospital130 enrolled2 locationsNCT06025331
Recruiting
Not Applicable

Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability?

Shoulder OsteoarthritisArthroplasty Complications
Lovisenberg Diakonale Hospital20 enrolled1 locationNCT06025448
Recruiting
Not Applicable

Retroversion in Reverse Shoulder Arthroplasty

Shoulder Osteoarthritis
Hospital Universitario Reina Sofia de Cordoba90 enrolled1 locationNCT05788614
Recruiting

Reverse or Anatomical replacement for Painful Shoulder Osteoarthritis (in adults 60 years and over): Differences between Interventions (RAPSODI-AUS)

Painful Shoulder Osteoarthritis
Deakin University430 enrolled25 locationsACTRN12622001364763
Recruiting
Phase 4

The efficacy of topical preparations in reducing the incidence of P. Acnes in total shoulder arthroplasty

Total Shoulder ArthroplastyShoulder Osteoarthritis
Orthopaedic Research Institute Queensland105 enrolled1 locationACTRN12618000261213