Phase 3 Chronic Obstructive Pulmonary Disease Clinical Trials
20 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 20 trials
Recruiting
Phase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled213 locationsNCT07190222
Recruiting
Phase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled215 locationsNCT07190209
Recruiting
Phase 3
Long-term Safety and Tolerability of Tozorakimab in Patients With COPD and History of Exacerbations
Chronic Obstructive Pulmonary DiseaseCOPD
AstraZeneca82 enrolled13 locationsNCT07566195
Recruiting
Phase 3
A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase III Study of HSK39004 Inhalation Powder for the Treatment of COPD
COPD, Chronic Obstructive Pulmonary Disease
Haisco Pharmaceutical Group Co., Ltd.376 enrolled1 locationNCT07583849
Recruiting
Phase 3
Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure
Chronic Obstructive Pulmonary Disease ExacerbationObstructive Sleep Apnea Exacerbation
Assistance Publique - Hôpitaux de Paris386 enrolled1 locationNCT07047092
Recruiting
Phase 3
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Hoffmann-La Roche2,000 enrolled486 locationsNCT05878769
Recruiting
Phase 3
Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination
PneumoniaCOPD, Chronic Obstructive Pulmonary Diseaseacute coronary syndromes (ACS)
University of Brawijaya60 enrolled1 locationNCT07604103
Recruiting
Phase 3
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
COPD, Chronic Obstructive Pulmonary Disease
AstraZeneca5,000 enrolled920 locationsNCT06283966
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca990 enrolled301 locationsNCT06883305
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca990 enrolled268 locationsNCT06878261
Recruiting
Phase 3
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
Hoffmann-La Roche1,290 enrolled462 locationsNCT05595642
Recruiting
Phase 2Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer1,156 enrolled32 locationsNCT07363694
Recruiting
Phase 3
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary DiseasePulmonary Hypertension
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT05844462
Recruiting
Phase 3
Multi-Center Clean Air Randomized Controlled Trial in COPD
Chronic Obstructive Pulmonary Disease (COPD)
JHSPH Center for Clinical Trials770 enrolled11 locationsNCT06376994
Recruiting
Phase 3
A Study to Evaluate the Safety and Efficacy of HL231 Solution for Inhalation in Patients with COPD
Chronic Obstructive Pulmonary Disease (COPD)
Haisco Pharmaceutical Group Co., Ltd.474 enrolled2 locationsNCT06643078
Recruiting
Phase 2Phase 3
Cell Therapy Associated With Endobronchial Valve
Chronic Obstructive Pulmonary Disease Severe
Hospital de Clinicas de Porto Alegre34 enrolled1 locationNCT04018729
Recruiting
Phase 3
Does blocking the body's own morphine-like chemicals during exercise change the perception of breathlessness?
Breathlessness during exercise in people with Chronic Obstructive Pulmonary Disease.
Flinders University- Deptment of Palliative and Supportive Services30 enrolled1 locationACTRN12611001182987
Completed
Phase 3
Microarray analysis following Anti-Inflammatory Interventions in Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary DiseaseEx-smokers with obstructive airway disease
Hunter New England Health Service15 enrolled1 locationACTRN12611000165987
Recruiting
Phase 3
Early inpatient-outpatient hospital-based pulmonary rehabilitation following hospitalisation for acute exacerbations of COPD: a randomised controlled study
Chronic Obstructive Pulmonary Disease (COPD)
Green Lane Research and Educational Fund100 enrolled1 locationACTRN12605000372684
Recruiting
Phase 3
Long term use of azithromycin for chronic lung disease in Aboriginal adults: a randomised controlled trial.
Chronic Obstructive Pulmonary Disease (COPD)
Menzies School of Health Research130 enrolled1 locationACTRN12605000229673