Phase 3 Chronic rhinosinusitis Clinical Trials
11 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–11 of 11 trials
Recruiting
Phase 3
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Sanofi210 enrolled121 locationsNCT06834347
Recruiting
Phase 3
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Sanofi210 enrolled113 locationsNCT06834360
Recruiting
Phase 3
A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
Chronic Rhinosinusitis With Nasal Polyps
AstraZeneca180 enrolled45 locationsNCT06706817
Recruiting
Phase 3
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Eli Lilly and Company510 enrolled194 locationsNCT06338995
Recruiting
Phase 3
Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps
Chronic Rhinosinusitis Without Nasal Polyps
Optinose US Inc.84 enrolled21 locationsNCT06850805
Recruiting
Phase 3
Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy
Chronic Rhinosinusitis (CRS)Cystic Fibrosis (CF)
Indiana University64 enrolled1 locationNCT06996951
Recruiting
Phase 3
Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd.246 enrolled60 locationsNCT07107256
Recruiting
Phase 3
Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal Polyps
Chronic Rhinosinusitis With Nasal Polyps
Guangdong Hengrui Pharmaceutical Co., Ltd280 enrolled1 locationNCT07132827
Recruiting
Phase 2Phase 3
Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS).
Chronic Rhinosinusitis With Nasal PolypsChronic Rhinosinusitis Without Nasal Polyps
Region Skane50 enrolled1 locationNCT07184684
Not Yet Recruiting
Phase 3
Effects of Chitodex with steroid on patients having sinus surgery for chronic rhinosinusitis
Chronic rhinosinusitis
Yuresh Naidoo31 enrolled4 locationsACTRN12621001507875
Not Yet Recruiting
Phase 3
Use of Dry Powder Mannitol for the Treatment of Chronic Rhinosinusitis
Chronic rhinosinusitis
Dr Emad Massoud40 enrolled1 locationACTRN12612001008819