Phase 2 Cognitive Clinical Trials
79 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 79 trials
Recruiting
Phase 2
Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate
SchizophreniaSchizo Affective DisorderSymptom, Cognitive
National Cheng-Kung University Hospital90 enrolled1 locationNCT06340789
Recruiting
Phase 2
Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV
Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled41 locationsNCT06705478
Recruiting
Phase 2
CBD for Individuals at Risk for Alzheimer's Disease
Mild Cognitive Impairment
University of Colorado, Denver236 enrolled1 locationNCT05822362
Recruiting
Phase 2
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases
CancerBrain Metastases, AdultNeurocognitive Function
Jona Hattangadi-Gluth60 enrolled1 locationNCT04343157
Recruiting
Phase 2
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
Alzheimer DiseaseMild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Massachusetts General Hospital40 enrolled1 locationNCT07236190
Recruiting
Phase 2
Equol and Vascular Function in Women With Chronic Kidney Disease
Cerebrovascular functionBlood PressureCognitive Functions+2 more
University of Colorado, Denver74 enrolled1 locationNCT07194590
Recruiting
Phase 2
Human Mesenchymal Stem Cells & Monoclonal Antibodies in the Treatment for Mild Cognitive Impairment or Early Alzheimer's Disease.
Mild Cognitive ImpairmentEarly Alzheimer's DiseaseAD-MCI
Bernard (Barry) Baumel10 enrolled1 locationNCT07512362
Recruiting
Phase 2
Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease
Alzheimer s DiseaseMild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Weill Medical College of Cornell University20 enrolled1 locationNCT07553338
Recruiting
Phase 2
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 2
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
Breast CancerBreast Cancer Stage IBreast Cancer Stage II+5 more
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT06727773
Recruiting
Phase 2
Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD)
Alzheimer DiseaseCognitive Decline, Mild
Helse Stavanger HF200 enrolled6 locationsNCT06362707
Recruiting
Phase 1Phase 2
FACE Phase II (a Stage II Trial)
MCIMild Behavioral ImpairmentSubjective Cognitive Decline (SCD)
Stanford University80 enrolled1 locationNCT07130669
Recruiting
Phase 1Phase 2
rTMS to Improve Cognition in Parkinson's
Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 1Phase 2
Stem Cell Therapy for Early Alzheimer's Disease
Cognitive Dysfunction
Paul E Schulz12 enrolled1 locationNCT06775964
Recruiting
Phase 2
Fisetin in Mild Alzheimer's Disease
Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+4 more
Sunnybrook Health Sciences Centre5 enrolled1 locationNCT07279714
Recruiting
Phase 2
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)
Neurocognitive FunctionPost-traumatic StressAcute Stress Disorder+1 more
University of North Carolina, Chapel Hill180 enrolled9 locationsNCT06636786
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 2
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
Alzheimer DiseaseCognitively Healthy People
Massachusetts Institute of Technology150 enrolled1 locationNCT07496918
Recruiting
Phase 2
Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Alzheimer DiseaseMild Cognitive Impairment
Chang Gung Memorial Hospital80 enrolled1 locationNCT06467539
Not Yet Recruiting
Phase 2
Cannabidiol and vitamin E on blood flow in the brain of older adults
Cognitive Decline
University of Southern Queensland80 enrolled1 locationACTRN12626000337370