Phase 2 Cognitive Clinical Trials
74 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 74 trials
Recruiting
Phase 1Phase 2
FACE Phase II (a Stage II Trial)
MCIMild Behavioral ImpairmentSubjective Cognitive Decline (SCD)
Stanford University80 enrolled1 locationNCT07130669
Recruiting
Phase 1Phase 2
rTMS to Improve Cognition in Parkinson's
Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 1Phase 2
Stem Cell Therapy for Early Alzheimer's Disease
Cognitive Dysfunction
Paul E Schulz12 enrolled1 locationNCT06775964
Recruiting
Phase 1Phase 2
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
Alzheimer DiseaseMild Cognitive Impairment (MCI)Subjective Cognitive Complaints (SCCs)
Massachusetts General Hospital40 enrolled1 locationNCT07236190
Recruiting
Phase 2
Fisetin in Mild Alzheimer's Disease
Alzheimer DiseaseAlzheimer DementiaAlzheimer Dementia (AD)+4 more
Sunnybrook Health Sciences Centre5 enrolled1 locationNCT07279714
Recruiting
Phase 2
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)
Neurocognitive FunctionPost-traumatic StressAcute Stress Disorder+1 more
University of North Carolina, Chapel Hill180 enrolled9 locationsNCT06636786
Recruiting
Phase 2
Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
DementiaHealthy VolunteersAlzheimer Disease+1 more
Akiva Mintz200 enrolled1 locationNCT07012993
Recruiting
Phase 2
Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV
Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled40 locationsNCT06705478
Recruiting
Phase 2
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
Alzheimer DiseaseCognitively Healthy People
Massachusetts Institute of Technology150 enrolled1 locationNCT07496918
Recruiting
Phase 2
Novel Augmentation of DAOIB and Antioxidant for Early Dementia
Alzheimer DiseaseMild Cognitive Impairment
Chang Gung Memorial Hospital80 enrolled1 locationNCT06467539
Not Yet Recruiting
Phase 2
Cannabidiol and vitamin E on blood flow in the brain of older adults
Cognitive Decline
University of Southern Queensland80 enrolled1 locationACTRN12626000337370
Recruiting
Phase 1Phase 2
Sense4Safety Intervention
Mild Cognitive Impairment
University of Pennsylvania200 enrolled1 locationNCT07220668
Recruiting
Phase 2
Repurposing Siponimod for Alzheimer's Disease
Alzheimer DiseaseCognitive Impairment, MildMild Alzheimer Disease+1 more
St. Joseph's Hospital and Medical Center, Phoenix105 enrolled1 locationNCT06639282
Recruiting
Phase 2
Cognitive Remediation Intervention to Prepare for Transition of Care
Cognitive ImpairmentSickle Cell DiseaseSelf Efficacy+3 more
University of Alabama at Birmingham120 enrolled1 locationNCT05336201
Recruiting
Phase 2
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
DepressionAnxietyDysautonomia+8 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting
Phase 2
Exercise to Improve Brain Health in Older African Americans
Cognitive ChangeAlzheimer DiseaseAging+1 more
Rutgers, The State University of New Jersey280 enrolled1 locationNCT05597124
Recruiting
Phase 2
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
DementiaAlzheimers DiseaseMild Cognitive Impairment Due to Alzheimer's Disease
Brigham and Women's Hospital16 enrolled1 locationNCT06489548
Recruiting
Phase 1Phase 2
The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment
ElderlyMild Cognitive ImpairmentOverweight or Obesity
Fudan University54 enrolled1 locationNCT07395960
Recruiting
Phase 2
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
Cognitive DysfunctionAlzheimer DiseaseFatty Acids, Omega-3+3 more
Michal Schnaider Beeri, Ph.D.20 enrolled1 locationNCT07392723
Recruiting
Phase 2
Senicapoc in Alzheimer's Disease
Alzheimer DiseaseMild Cognitive Impairment
University of California, Davis55 enrolled2 locationsNCT04804241