Phase 1 Colitis Clinical Trials
30 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 30 trials
Recruiting
Phase 1
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 1Phase 2
A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis
Moderate to Severe Ulcerative Colitis
Genentech, Inc.24 enrolled1 locationNCT06693908
Recruiting
Phase 1Phase 2
A Study of MB-001 in Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)
Mage Biologics100 enrolled1 locationNCT07374471
Recruiting
Phase 1
KAN-004 for Immune-Related Diarrhea or Colitis
ColitisDiarrhea Caused by Antitumor Drugs
Centre hospitalier de l'Université de Montréal (CHUM)21 enrolled1 locationNCT07196410
Recruiting
Phase 1Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Ulcerative Colitis (UC)
Xencor, Inc.270 enrolled52 locationsNCT06619990
Recruiting
Phase 1Phase 2
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC)
Necrotizing Enterocolitis
Noveome Biotherapeutics, formerly Stemnion36 enrolled8 locationsNCT06315738
Recruiting
Phase 1Phase 2
Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis
Chronic Granulomatous Disease-associated Colitis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT05333471
Not Yet Recruiting
Phase 1
A randomised controlled trial to evaluate the drug TL-003 in healthy adults aged 18-55.
Ulcerative Colitis
SAPRO Consulting Pty Ltd.64 enrolled1 locationACTRN12626000354381
Recruiting
Phase 1
Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
Breast CancerOvarian CancerCervical Cancer+6 more
M.D. Anderson Cancer Center40 enrolled1 locationNCT04038619
Recruiting
Phase 1Phase 2
FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Ulcerative ColitisClostridium Difficile
Fondazione Policlinico Universitario Agostino Gemelli IRCCS64 enrolled1 locationNCT06071312
Recruiting
Phase 1Phase 2
Superdonor FMT in Patients With Ulcerative Colitis
Active Ulcerative Colitis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS42 enrolled1 locationNCT05739864
Recruiting
Phase 1
Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+41 more
M.D. Anderson Cancer Center800 enrolled1 locationNCT03819296
Recruiting
Phase 1
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
Ulcerative ColitisUlcerative Colitis ChronicUlcerative Colitis Chronic Mild+1 more
Rise Therapeutics LLC36 enrolled4 locationsNCT05666960
Recruiting
Phase 1
Evaluate the Safety, Tolerability, PK and PD of SAD of Intravenously Adminsterted ALTB-268 in Healthy Participants
Ulcerative Colitis (UC)
AltruBio Inc.24 enrolled1 locationNCT07350577
Recruiting
Phase 1
A Study of SER-155 to Treat Diarrhea in People on Immunotherapy
DiarrheaEnterocolitis
Memorial Sloan Kettering Cancer Center15 enrolled7 locationsNCT06801067
Recruiting
Phase 1Phase 2
A Study of AC-101 Tablets in Participants With Moderate to Severe Active Ulcerative Colitis
Ulcerative Colitis
Accro Bioscience (Suzhou) Limited24 enrolled1 locationNCT07083193
Recruiting
Phase 1Phase 2
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy
Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Children's Hospital Medical Center, Cincinnati116 enrolled3 locationsNCT03847467
Recruiting
Phase 1Phase 2
Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease
Ulcerative Colitis (UC)Crohn Disease (CD)
University Medical Center Groningen18 enrolled1 locationNCT06606808
Recruiting
Phase 1
A Study of NP-201 Acetate Injection in Healthy Adult Volunteers and in Patients With Mild-To-Moderate Active Ulcerative Colitis
Active Ulcerative ColitisActive Ulcerative Colitis (UC)Healthy Adult Volunteers
NIBEC Co., Ltd.24 enrolled1 locationNCT06681389
Not Yet Recruiting
Phase 1
The Pharmacokinetics and the Effect of Extended-release Thioguanine Tablets on Symptoms in Adults with Ulcerative Colitis.
Inflammatory Bowel DiseaseActive Ulcerative Colitis
Douglas Pharmaceuticals12 enrolled1 locationACTRN12624001448538