Phase 2 Colitis Clinical Trials
60 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 60 trials
Recruiting
Phase 2
A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis
Colitis Ulcerative
Sanofi204 enrolled115 locationsNCT06867094
Recruiting
Phase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
ColitisInflammatory Bowel DiseasesUlcerative Colitis
Spyre Therapeutics, Inc.645 enrolled175 locationsNCT07012395
Recruiting
Phase 2
A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis
Ulcerative Colitis
Sanofi99 enrolled67 locationsNCT06975722
Recruiting
Phase 2
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Ulcerative ColitisColitis Ulcerative
Merck Sharp & Dohme LLC100 enrolled7 locationsNCT07463183
Recruiting
Phase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)Ulcerative Colitis, Active ModerateUlcerative Colitis, Active Severe
Eli Lilly and Company1,431 enrolled251 locationsNCT07415044
Recruiting
Phase 2
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
Ulcerative ColitisUlcerative Colitis Chronic
Eli Lilly and Company140 enrolled207 locationsNCT06598943
Recruiting
Phase 2
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Ulcerative Colitis
Eli Lilly and Company252 enrolled149 locationsNCT07186101
Recruiting
Phase 1Phase 2
A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis
Moderate to Severe Ulcerative Colitis
Genentech, Inc.24 enrolled1 locationNCT06693908
Recruiting
Phase 1Phase 2
A Study of MB-001 in Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)
Mage Biologics100 enrolled1 locationNCT07374471
Recruiting
Phase 2
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis
Takeda207 enrolled141 locationsNCT06254950
Recruiting
Phase 1Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Ulcerative Colitis (UC)
Xencor, Inc.270 enrolled52 locationsNCT06619990
Recruiting
Phase 1Phase 2
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC)
Necrotizing Enterocolitis
Noveome Biotherapeutics, formerly Stemnion36 enrolled8 locationsNCT06315738
Recruiting
Phase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Ulcerative Colitis
Genentech, Inc.224 enrolled64 locationsNCT06979336
Recruiting
Phase 1Phase 2
Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis
Chronic Granulomatous Disease-associated Colitis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT05333471
Recruiting
Phase 2
Study Evaluating ISM5411 Administered Orally to Subjects With Active Ulcerative Colitis (BETHESDA)
Ulcerative Colitis
InSilico Medicine Hong Kong Limited80 enrolled28 locationsNCT07265570
Recruiting
Phase 2
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Ulcerative Colitis
Pfizer36 enrolled47 locationsNCT05287126
Recruiting
Phase 2
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Ulcerative Colitis (UC)
Northwestern University180 enrolled1 locationNCT07427017
Recruiting
Phase 1Phase 2
FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Ulcerative ColitisClostridium Difficile
Fondazione Policlinico Universitario Agostino Gemelli IRCCS64 enrolled1 locationNCT06071312
Recruiting
Phase 1Phase 2
Superdonor FMT in Patients With Ulcerative Colitis
Active Ulcerative Colitis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS42 enrolled1 locationNCT05739864
Recruiting
Phase 2
Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease
Crohn DiseaseUlcerative Colitis (UC)IBD
Assistance Publique - Hôpitaux de Paris45 enrolled1 locationNCT07300553