Phase 3 Colitis Clinical Trials
26 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 26 trials
Recruiting
Phase 3
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Crohn's DiseaseUlcerative Colitis
Takeda240 enrolled98 locationsNCT05442567
Recruiting
Phase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis
Sanofi671 enrolled20 locationsNCT07185009
Recruiting
Phase 3
Vancomycin Taper to Prevent Recurrent Clostridioides Difficile
Clostridia Difficile Colitis
McGill University Health Centre/Research Institute of the McGill University Health Centre500 enrolled1 locationNCT07328971
Recruiting
Phase 3
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis
Sanofi980 enrolled191 locationsNCT07184996
Recruiting
Phase 3
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis
Moderately to Severely Active Ulcerative Colitis
Hoffmann-La Roche100 enrolled9 locationsNCT07158242
Recruiting
Phase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Ulcerative ColitisObesity or Overweight
Eli Lilly and Company350 enrolled191 locationsNCT06937086
Recruiting
Phase 3
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Inflammatory Bowel DiseasesCrohn's DiseaseUlcerative Colitis+1 more
Eli Lilly and Company150 enrolled66 locationsNCT04844606
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
Moderately to Severely Active Ulcerative Colitis
Hoffmann-La Roche350 enrolled198 locationsNCT06588855
Recruiting
Phase 3
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab
Ulcerative Colitis
AbbVie530 enrolled270 locationsNCT06880744
Recruiting
Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis
Ulcerative Colitis
Eli Lilly and Company60 enrolled34 locationsNCT05784246
Recruiting
Phase 3
Transfer of FRozen Encapsulated Multidonor Stool Filtrate for Active Ulcerative COlitis
Inflammatory Bowel DiseasesUlcerative Colitis
Andreas Stallmach129 enrolled20 locationsNCT03843385
Recruiting
Phase 3
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Ulcerative Colitis
AbbVie120 enrolled33 locationsNCT07071519
Recruiting
Phase 3
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Ulcerative Colitis
Alfasigma S.p.A.80 enrolled51 locationsNCT06865417
Recruiting
Phase 3
Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis
Moderately to Severely Active Ulcerative Colitis
Takeda402 enrolled36 locationsNCT03221036
Recruiting
Phase 3
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled1 locationNCT06405087
Recruiting
Phase 3
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled57 locationsNCT06100289
Recruiting
Phase 2Phase 3
Evaluate the Efficacy and Safety of Probiotic 6600 as an Adjuvant Therapy for Colitis
ColitisIBD (Inflammatory Bowel Disease)Probiotic Intervention
Changhai Hospital120 enrolled1 locationNCT07047339
Not Yet Recruiting
Phase 2Phase 3
Oral vancomycin for treating atypical gut inflammation in children
Primary sclerosing cholangitis - ulcerative colitisAtypical ulcerative colitis
Queensland Children's Hospital63 enrolled1 locationACTRN12624001372572
Recruiting
Phase 2Phase 3
Efficacy and Safety of Oral Controlled-Ileocolonic-Release Nicotinamide (CICR-NAM) in Patients with Mild to Moderately Active Ulcerative Colitis
Ulcerative Colitis, Unspecified
University Hospital Schleswig-Holstein459 enrolled1 locationNCT06488625
Recruiting
Phase 2Phase 3
Unravelling Intestinal Fibrosis in Ulcerative Colitis
Fibroblast Activation Protein InhibitorUlcerative Colitis (UC)Inflammatory Bowel Disease (IBD)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)10 enrolled1 locationNCT06604273