Phase 1 Colon Cancer Clinical Trials
16 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–16 of 16 trials
Recruiting
Phase 1
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
Breast CancerCervical CancerColon Cancer+4 more
Orano Med LLC48 enrolled4 locationsNCT05283330
Recruiting
Phase 1Phase 2
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)110 enrolled1 locationNCT03190941
Recruiting
Phase 1
A Study of PHN-012 in Patients With Advanced Solid Tumors
Pancreatic CancerColon CancerAdvanced Cancer+2 more
Pheon Therapeutics165 enrolled21 locationsNCT07127874
Recruiting
Phase 1
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma+37 more
National Cancer Institute (NCI)51 enrolled23 locationsNCT04704661
Recruiting
Phase 1
A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
Pancreatic CancerLung CancerColon Cancer+3 more
RasCal Therapeutics, Inc.134 enrolled3 locationsNCT04678648
Recruiting
Phase 1
CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors
Esophageal CancerGastric CancerLung Cancer+3 more
Chongqing Precision Biotech Co., Ltd108 enrolled1 locationNCT07179692
Recruiting
Phase 1Phase 2
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT03745326
Recruiting
Phase 1
A Phase I, Autologous ex Vivo Expanded and Activated NK Cell, Magicell-NK, Infusion for Colon Cancer Post Resection Study
Colon Cancer Stage I
Medigen Biotechnology Corporation18 enrolled1 locationNCT05394714
Recruiting
Phase 1
A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors
Breast CancerPancreatic CancerGastric Cancer+6 more
GONGCHU Biotechnology Co., Ltd21 enrolled1 locationNCT06508307
Recruiting
Phase 1Phase 2
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+4 more
ModeX Therapeutics, An OPKO Health Company115 enrolled6 locationsNCT06239194
Recruiting
Phase 1
Brodalumab in the Treatment of Immune-Related Adverse Events
Breast CancerLiver CancerEsophageal Cancer+15 more
Brian Henick, MD11 enrolled1 locationNCT06673329
Recruiting
Phase 1
A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors
Colon CancerMetastatic Colon Cancer
Sapience Therapeutics130 enrolled11 locationsNCT05848739
Recruiting
Phase 1Phase 2
CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+4 more
Chongqing Precision Biotech Co., Ltd60 enrolled3 locationsNCT06006390
Recruiting
Phase 1Phase 2
Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars
Colon Cancer
University Hospital, Linkoeping300 enrolled1 locationNCT06270017
Recruiting
Phase 1
Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors
Breast CancerGastric CancerCholangiocarcinoma+5 more
Chongqing Precision Biotech Co., Ltd60 enrolled1 locationNCT06126406
Recruiting
Phase 1
Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors
Breast CancerGastric CancerCholangiocarcinoma+4 more
Chongqing Precision Biotech Co., Ltd36 enrolled1 locationNCT06010862