Phase 1 Colon Cancer Clinical Trials

12 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 112 of 12 trials

Recruiting
Phase 1

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

Pancreatic CancerLung CancerColon Cancer+3 more
RasCal Therapeutics, Inc.134 enrolled3 locationsNCT04678648
Recruiting
Phase 1

A Study of PHN-012 in Patients With Advanced Solid Tumors

Pancreatic CancerColon CancerAdvanced Cancer+2 more
Pheon Therapeutics165 enrolled7 locationsNCT07127874
Recruiting
Phase 1

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

Breast CancerCervical CancerColon Cancer+4 more
Orano Med LLC48 enrolled4 locationsNCT05283330
Recruiting
Phase 1

CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors

Esophageal CancerGastric CancerLung Cancer+3 more
Chongqing Precision Biotech Co., Ltd108 enrolled1 locationNCT07179692
Recruiting
Phase 1Phase 2

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients

Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT03745326
Recruiting
Phase 1

A Phase I Clinical Study of Intratumoral Injection Oncolytic Vaccinia Virus GC001 in Patient With Advanced Solid Tumors

Breast CancerPancreatic CancerGastric Cancer+6 more
GONGCHU Biotechnology Co., Ltd21 enrolled1 locationNCT06508307
Recruiting
Phase 1Phase 2

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+4 more
ModeX Therapeutics, An OPKO Health Company115 enrolled6 locationsNCT06239194
Recruiting
Phase 1

Brodalumab in the Treatment of Immune-Related Adverse Events

Breast CancerLiver CancerEsophageal Cancer+15 more
Brian Henick, MD11 enrolled1 locationNCT06673329
Recruiting
Phase 1Phase 2

CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+4 more
Chongqing Precision Biotech Co., Ltd60 enrolled3 locationsNCT06006390
Recruiting
Phase 1Phase 2

Evaluation of Metastatic Disease and Oncological Treatment in Patients With Colon Cancer Using Zebra Fish Avatars

Colon Cancer
University Hospital, Linkoeping300 enrolled1 locationNCT06270017
Recruiting
Phase 1

Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes(CAR-T) for CEA Positive Advanced Malignant Solid Tumors

Breast CancerGastric CancerCholangiocarcinoma+5 more
Chongqing Precision Biotech Co., Ltd60 enrolled1 locationNCT06126406
Recruiting
Phase 1

Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors

Breast CancerGastric CancerCholangiocarcinoma+4 more
Chongqing Precision Biotech Co., Ltd36 enrolled1 locationNCT06010862