Phase 2 Colon Cancer Clinical Trials
32 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 32 trials
Recruiting
Phase 1Phase 2
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)110 enrolled1 locationNCT03190941
Recruiting
Phase 2Phase 3
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Stage III Colon Cancer
NRG Oncology1,912 enrolled1054 locationsNCT05174169
Recruiting
Phase 2
Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment
Colorectal CarcinomaStage I Colorectal Cancer AJCC v8Stage II Colorectal Cancer AJCC v8+9 more
Emory University38 enrolled4 locationsNCT07405476
Recruiting
Phase 2Phase 3
Adjuvant mFOLFIRINOX for High-risk Stage III Colon Cancer
Colon Cancer Stage III
Chungnam National University Hospital308 enrolled1 locationNCT05179889
Recruiting
Phase 2
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)
Colon CancerRectal Cancer
SCRI Development Innovations, LLC60 enrolled14 locationsNCT07011576
Recruiting
Phase 2
Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
Colon CancerRectal Cancer
Rutgers, The State University of New Jersey50 enrolled9 locationsNCT05806931
Recruiting
Phase 2
Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study)
Colon Cancer
Institute of Oncology Ljubljana100 enrolled1 locationNCT07432399
Recruiting
Phase 2
Phase II Trial of Lung Chemoemobolization
SarcomaColon CancerLung Non-Small Cell Carcinoma+4 more
City of Hope Medical Center30 enrolled2 locationsNCT05672108
Recruiting
Phase 2
Phase II Study of Neoadjuvant Dostarlimab in Patients With Untreated T3-4N0-2 or Stage III pMMR/MSS Resectable Colon Cancer
Colon Cancer Stage III
Universitaire Ziekenhuizen KU Leuven10 enrolled1 locationNCT06830239
Recruiting
Phase 2
Effect of Perioperative Intravenous Infusion of Lidocaine on the Postoperative Course and the Immune Response in Patients Undergoing Surgery for Colon Cancer - the PILDI Study
Colon Cancer
Institute of Oncology Ljubljana100 enrolled2 locationsNCT06923787
Recruiting
Phase 2
Microbiotic Product to Promote Microbiome Health and Improve Chemotherapy Delivery
Metastatic Colon CarcinomaStage IV Colon Cancer AJCC v8Stage IVA Colon Cancer AJCC v8+2 more
Howard S. Hochster, MD42 enrolled10 locationsNCT05296681
Recruiting
Phase 2
FMT+ QL1706+Bevacizumab+ XELOX as First-line Treatment for Advanced MSS-type Colon Cancer With Liver Metastasis
Colon Cancer Liver Metastases
Hua Jiang30 enrolled1 locationNCT06801665
Recruiting
Phase 2
Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial
Colon CancerRadiation TherapyNeoadjuvant Therapies+1 more
Sixth Affiliated Hospital, Sun Yat-sen University38 enrolled1 locationNCT07279077
Recruiting
Phase 2Phase 3
Colon Cancer Diagnosis With FAPI-PET Imaging
Colon Cancer
Turku University Hospital100 enrolled1 locationNCT07272772
Recruiting
Phase 2
The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer
Colon Cancer
M.D. Anderson Cancer Center50 enrolled5 locationsNCT05961709
Recruiting
Phase 2
Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer
Stage III Colon Cancer AJCC v8Localized Colon CarcinomaStage IIB Colon Cancer AJCC v8+1 more
Emory University40 enrolled5 locationsNCT07140679
Recruiting
Phase 1Phase 2
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Pancreatic CancerGastric CancerColon Cancer+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT03745326
Recruiting
Phase 2
Neoadjuvant Chemotherapy Plus Sequential Immune Checkpoint Inhibitor (ICI) Therapy in Locally Advanced Colon Cancer
Colon Cancer
Ruijin Hospital56 enrolled1 locationNCT06368141
Recruiting
Phase 2
Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）
Colon Cancer
Hebei Medical University Fourth Hospital128 enrolled1 locationNCT06949111
Recruiting
Phase 2
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Pancreatic CancerGastric CancerLung Cancer+15 more
Apollomics Inc.497 enrolled35 locationsNCT03175224