Phase 1 Colorectal Cancer Metastatic Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

Colorectal Cancer MetastaticLung Metastases
University Health Network, Toronto10 enrolled1 locationNCT05611034
Recruiting
Phase 1Phase 2

Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer

Colorectal Cancer MetastaticAdenocarcinoma of Colon
Beijing Biotech48 enrolled1 locationNCT07462650
Recruiting
Phase 1Phase 2

A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer

Colorectal Cancer Metastatic
Carina Biotech Limited45 enrolled1 locationNCT05759728
Recruiting
Phase 1Phase 2

A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

ImmunotherapyColorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc.66 enrolled15 locationsNCT07244705
Recruiting
Phase 1Phase 2

ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC

Colorectal Cancer Metastatic
Sun Yat-sen University64 enrolled1 locationNCT07012954
Recruiting
Phase 1Phase 2

XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.

Biliary Tract CancerOvarian CancerGastric Carcinoma+4 more
Evopoint Biosciences Inc.240 enrolled1 locationNCT06792435
Recruiting
Phase 1

A Study of NILK-2301 in Patients with Locally Advanced or Metastatic Low Tumor Volume (LTV) Colorectal Cancer

Colorectal Cancer Metastatic
Light Chain Bioscience - Novimmune SA25 enrolled2 locationsNCT06663839
Recruiting
Phase 1Phase 2

Galunisertib Combined With Capecitabine in Advanced CRC With PM

Peritoneal CarcinomatosisColorectal Cancer Metastatic
The Netherlands Cancer Institute31 enrolled2 locationsNCT05700656
Recruiting
Phase 1Phase 2

Trifluridine/Tipiracil Combined With Cetuximab in the Treatment of Third-line and Above RAS/BRAF Wild-type mCRC

Colorectal Cancer Metastatic
Wangxia LV26 enrolled1 locationNCT06379399