Phase 2 Colorectal Cancer Metastatic Clinical Trials
29 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 29 trials
Recruiting
Phase 2
TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer
Colorectal Cancer MetastaticAdvanced Colorectal Cancer
Suzhou Teligene Ltd.80 enrolled1 locationNCT06589830
Recruiting
Phase 2
Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
Liver MetastasesColorectal Cancer Metastatic
Weill Medical College of Cornell University24 enrolled1 locationNCT06300463
Recruiting
Phase 2
Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)
Colorectal Cancer Metastatic
Buzzard Pharmaceuticals20 enrolled2 locationsNCT06634875
Recruiting
Phase 1Phase 2
Dual-Target CAR-NK Cells for Biomarker-Selected Advanced Colorectal Cancer
Colorectal Cancer MetastaticAdenocarcinoma of Colon
Beijing Biotech48 enrolled1 locationNCT07462650
Recruiting
Phase 2
Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy
Colorectal Cancer MetastaticIntrahepatic Cholangiocarcinoma
Michael J Cavnar, MD80 enrolled1 locationNCT07201519
Recruiting
Phase 1Phase 2
A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer
Colorectal Cancer Metastatic
Carina Biotech Limited45 enrolled1 locationNCT05759728
Recruiting
Phase 2
STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal Cancer
Colorectal Cancer Metastatic
National Cancer Institute, Naples60 enrolled1 locationNCT07213570
Recruiting
Phase 2
ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal Cancer
Colorectal Cancer Metastatic
National Cancer Institute, Naples130 enrolled8 locationsNCT06714357
Recruiting
Phase 2
Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab
Colorectal Cancer Metastatic
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled1 locationNCT06540326
Recruiting
Phase 2
A Phase II Clinical Study of Multimodal Ablation Combined With Systemic Drug Therapy for Advanced Solid Tumors.
Triple Negative Breast Cancer MetastaticMelanoma MetastaticColorectal Cancer Metastatic
Fudan University95 enrolled1 locationNCT06889610
Recruiting
Phase 1Phase 2
A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC
ImmunotherapyColorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc.66 enrolled15 locationsNCT07244705
Recruiting
Phase 2
Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer
ChemotherapyTargeted TherapyImmunotherapy+2 more
Sun Yat-sen University57 enrolled1 locationNCT06764680
Recruiting
Phase 2
Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer
Colorectal Cancer MetastaticPancreatic Cancer MetastaticPancreatic Cancer Non-resectable
HealthPartners Institute64 enrolled1 locationNCT06605430
Recruiting
Phase 2
Clinical Study of Irinotecan Liposome (II)-Based Combination Treatment for Irinotecan-resistant Colorectal Cancer.
Colorectal Cancer Metastatic
Chinese PLA General Hospital30 enrolled1 locationNCT07044921
Recruiting
Phase 1Phase 2
ctDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC
Colorectal Cancer Metastatic
Sun Yat-sen University64 enrolled1 locationNCT07012954
Recruiting
Phase 2
FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients
Colorectal Cancer Metastatic
Sun Yat-sen University194 enrolled1 locationNCT05727163
Recruiting
Phase 2
Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer
Colorectal Cancer Metastatic
Fudan University36 enrolled1 locationNCT06763029
Recruiting
Phase 2
Cryoablation Combined with Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis
Liver MetastasesColorectal Cancer Metastatic
Fudan University25 enrolled1 locationNCT05057052
Recruiting
Phase 2
Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer
Colorectal Cancer Metastatic
The Fourth Affiliated Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT06282445
Recruiting
Phase 1Phase 2
XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies.
Biliary Tract CancerOvarian CancerGastric Carcinoma+4 more
Evopoint Biosciences Inc.240 enrolled1 locationNCT06792435