Early Phase 1 Colorectal Clinical Trials
12 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–12 of 12 trials
Recruiting
Early Phase 1
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis
Massachusetts General Hospital15 enrolled1 locationNCT07128355
Recruiting
Early Phase 1
INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases
Colorectal Cancer Metastatic
Northwell Health10 enrolled1 locationNCT07172282
Recruiting
Early Phase 1
Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis
Colorectal Cancer Metastatic
Northwell Health10 enrolled2 locationsNCT07193862
Recruiting
Early Phase 1
Universal CAR-T Cells (REVO-UWD-01) for Metastatic Colorectal Cancer
Metastatic Colorectal CancerCRC (Colorectal Cancer)
Wondercel Biotech (ShenZhen)30 enrolled2 locationsNCT06653010
Recruiting
Early Phase 1
Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer.
Colorectal, CancerDC-CIK TreatmentRegorafenib+2 more
JIANG LONGWEI14 enrolled1 locationNCT07343791
Recruiting
Early Phase 1
COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer
Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd.12 enrolled1 locationNCT07328087
Recruiting
Early Phase 1
Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy
Metastatic Colorectal Cancer (CRC)Oxaliplatin Induced Peripheral Neuropathy in Cancer PatientsPeripheral Neuropathy Due to Chemotherapy
Fox Chase Cancer Center30 enrolled1 locationNCT07167446
Recruiting
Early Phase 1
A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer
Colorectal Cancer MetastaticColorectal Cancer RecurrentColorectal Cancer Stage IV
Shanghai Changzheng Hospital20 enrolled1 locationNCT07050394
Recruiting
Early Phase 1
Autologous CAR-T Cells (WD-01) for Metastatic Colorectal Cancer
Metastatic Colorectal CancerCRC (Colorectal Cancer)
Wondercel Biotech (ShenZhen)30 enrolled2 locationsNCT06675513
Recruiting
Early Phase 1
A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients
Metastatic Colorectal Cancer (Mcrc)
Shanghai Changzheng Hospital9 enrolled1 locationNCT06621173
Recruiting
Early Phase 1
CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors
Biliary Tract CancerColorectal CarcinomaGastric Cancer, Metastatic+2 more
Zhejiang University18 enrolled1 locationNCT06937567
Recruiting
Early Phase 1
Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer
Advanced Colorectal Cancer
Shanghai East Hospital30 enrolled1 locationNCT06446050