Phase 4 Colorectal Clinical Trials

16 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 116 of 16 trials

Recruiting
Phase 4

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

Colorectal, Cancer
Takeda78 enrolled45 locationsNCT06562543
Recruiting
Phase 4

Fluid Challenge and Plasma Volume, During Surgery

Colorectal, CancerGynecologic CancerUrologic Cancer+2 more
Joachim Zdolsek60 enrolled1 locationNCT05726136
Recruiting
Phase 4

Multi-center Randomized Controlled Clinical Study of Shenling Baishu Granule to Prevent the Recurrence of Low-risk Colorectal Adenoma

Low-risk Colorectal Adenoma
Shanghai Jiao Tong University School of Medicine624 enrolled1 locationNCT06930157
Recruiting
Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Breast NeoplasmsColorectal NeoplasmsHead and Neck Neoplasms+1 more
Rutgers, The State University of New Jersey100 enrolled12 locationsNCT07158164
Recruiting
Phase 4

Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial

Colorectal Cancer ScreeningBowel Cleansing for Colonoscopy
Morehouse School of Medicine300 enrolled1 locationNCT07215000
Recruiting
Phase 4

Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure

Colorectal DisordersSurgical Site InfectionWound Surgical
University of Nevada, Las Vegas84 enrolled1 locationNCT06309368
Recruiting
Phase 4

Prevention of Recurrence and Metastasis of Colorectal Cancer by Comparing Huaier With Capecitabine Monotherapy

Colorectal, Cancer
Fudan University756 enrolled9 locationsNCT06090994
Recruiting
Phase 4

Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery

Colorectal CarcinomaAnalgesia, PostoperativeLaparotomy
Meri Mirceta98 enrolled1 locationNCT06935708
Recruiting
Phase 4

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Carcinoma
Guang'anmen Hospital of China Academy of Chinese Medical Sciences320 enrolled1 locationNCT05894694
Recruiting
Phase 4

Safety and Efficacy of Pembrolizumab in Combination with Bevacizumab + CapeOX in the Neoadjuvant Treatment of RAS-mutated, BRAF Wild-type, Microsatellite-stabilized, Locally Advanced Colorectal Cancer

Locally Advanced Colorectal Cancer
yangjianjun20 enrolled1 locationNCT06550453
Recruiting
Phase 4

Bowel Preparation in Colonoscopy: Lactulose Vs Polyethyleneglycol, Randomized Double-blind Comparative Clinical Trial, Multicenter Study.

Colorectal Cancer Screening
Hospital Civil de Guadalajara300 enrolled3 locationsNCT06666556
Recruiting
Phase 4

TES RCT Fleet Enema vs Oral Mechanical Bowel Prep

SurgeryColorectal Neoplasms
Nova Scotia Health Authority66 enrolled1 locationNCT05148494
Recruiting
Phase 4

Clinical Study of Fruquintinib Combined With Raltitrexed in the Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
The First Affiliated Hospital of Nanchang University30 enrolled1 locationNCT06118762
Recruiting
Phase 4

STIMUlant and osmotic LAXatives in Postoperative Ileus

Postoperative ComplicationsColorectal SurgeryPostoperative Ileus
The Royal Adelaide Hospital154 enrolled1 locationACTRN12618001261202
Completed
Phase 4

Postoperative analgesia of continuous wound catheters and ultrasound guided rectus sheath catheters for colorectal surgery.

Post-operative pain following elective open colorectal surgery
Hoda Alsaid Ahmed Ezz60 enrolled1 locationACTRN12615000636550
Completed
Phase 4

Efficacy of continuous preperitoneal infusion of ropivacaine in laparoscopic colorectal surgery

This study investigates postoperative analgesic efficacy and recovery in patients receiving continuous preperitoneal ropivacaine infusion vs. intravenous patient controlled analgesia after laparoscopic colorectal surgery.
Samsung Medical Center46 enrolled1 locationACTRN12611000183987