RecruitingPhase 4NCT05894694

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Survival Benefit of Compound Kushen Injection in Treatment of Advanced Colorectal Cancer Based on Real World Registration Platform


Sponsor

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Enrollment

320 participants

Start Date

Sep 27, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

To clarify the effectiveness and safety of compound kushen injection in the treatment of advanced colorectal cancer.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines whether adding Compound Kushen Injection (a traditional Chinese herbal medicine) to standard chemotherapy improves survival and quality of life for people with advanced colorectal cancer receiving first-line treatment. **You may be eligible if...** - You are 18 or older - You have advanced colorectal cancer confirmed by pathology and are receiving first-line (initial) therapy - You have a good performance status (ECOG 0–2) - You have at least one measurable tumor lesion - Your expected survival is at least 3 months **You may NOT be eligible if...** - You are receiving treatment other than first-line therapy - You have no measurable tumor - Your expected survival is less than 3 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGfirst-line scheme+compound kushen injection

FOLFOX/FOLFIRI/CAPEOX± Cetuximab/bevacizumab+compound kushen injection Compound Kushen injection: intravenous infusion, 20ml at a time, diluted with 200ml sodium chloride injection, once a day, each cycle of chemotherapy should reach the cumulative dose of 200ml.

DRUGpalliative care group first-line scheme

FOLFOX/FOLFIRI/CAPEOX± Cetuximab/bevacizumab


Locations(1)

Guang 'anmen Hospital, China Academy of Chinese Medical Sciences

Beijing, China

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NCT05894694


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