Phase 2 Cornea Clinical Trials

12 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 112 of 12 trials

Recruiting
Phase 2

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Corneal Transplant Failure
Massachusetts Eye and Ear Infirmary96 enrolled12 locationsNCT06753916
Recruiting
Phase 2

Lacripep for Corneal Wound Healing Study

Corneal Epithelial Wound Healing
Henry M. Jackson Foundation for the Advancement of Military Medicine88 enrolled1 locationNCT06854393
Recruiting
Phase 2

Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease

Persistent Corneal Epithelial DefectCorneal Epithelial Disorders
University of Illinois at Chicago24 enrolled1 locationNCT06919081
Recruiting
Phase 1Phase 2

Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.

Herpes Simplex KeratitisCorneal Neovascularization
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled1 locationNCT07329686
Recruiting
Phase 2

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal DystrophyFuchs
Design Therapeutics, Inc.28 enrolled2 locationsNCT07024693
Recruiting
Phase 2

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

corneal ulcer
University of Illinois at Chicago38 enrolled4 locationsNCT05705024
Recruiting
Phase 2

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia

Corneal EctasiaKeratoconusPellucid Marginal Corneal Degeneration
Goodman Eye Center500 enrolled1 locationNCT04094090
Recruiting
Phase 2

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Massachusetts Eye and Ear Infirmary45 enrolled1 locationNCT04440280
Recruiting
Phase 2Phase 3

Corneal Crosslinking for Treatment of Corneal Neovascularization

Corneal Neovascularization
Price Vision Group62 enrolled1 locationNCT04787471
Recruiting
Phase 2Phase 3

Comparison of Standard vs. Accelerated Corneal Crosslinking

KeratoconusEctasia Corneal
Price Vision Group510 enrolled1 locationNCT03922542
Recruiting
Phase 2

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED

Persistent Corneal Epithelial Defect
Glaukos Corporation84 enrolled28 locationsNCT05966493
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple Myeloma

NeoplasmsMultiple MyelomaParaproteinemias+5 more
Hellenic Society of Hematology36 enrolled2 locationsNCT05573802