Cough Clinical Trials

51 recruitingLast updated: June 18, 2026

There are 51 actively recruiting cough clinical trials across 26 countries. Studies span Not Applicable, Phase 3, Phase 4, Early Phase 1, Phase 1, Phase 2. Top locations include Hamilton, Ontario, Canada, Missoula, Montana, United States, Charleston, South Carolina, United States. Updated daily from ClinicalTrials.gov.


Cough Trials at a Glance

51 actively recruiting trials for cough are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Hamilton, Missoula, and Charleston. Lead sponsors running cough studies include McMaster University, University of Montana, and Association Clinique Thérapeutique Infantile du val de Marne.

Treatments under study

About Cough Clinical Trials

Looking for clinical trials for Cough? There are currently 21 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cough trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cough clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 51 trials

Recruiting
Not Applicable

Evaluating the Feasibility and Reliability of Using Handheld Nebulizers to Conduct Cough Sensitivity Testing With Citric Acid

Cough Reflex Sensitivity
University of Montana10 enrolled1 locationNCT07531901
Recruiting
Not Applicable

Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?

Neuromuscular DiseasesCoughAirway Clearance Impairment
Cliniques universitaires Saint-Luc- Université Catholique de Louvain40 enrolled1 locationNCT06190431
Recruiting
Not Applicable

Acupressure for Cough in Lung Cancer Survivors

Lung Cancer (Diagnosis)AcupressureSymptom Cluster+1 more
The University of Hong Kong80 enrolled2 locationsNCT07315672
Recruiting
Phase 3

Finnish Children´s Protracted Cough

chronic cough
Tampere University Hospital100 enrolled1 locationNCT07582549
Recruiting

Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough

Cough
University of Alabama at Birmingham50 enrolled1 locationNCT04642352
Recruiting
Phase 4

Evaluation of Treatments for Dry or Productive Cough

Cough
University Hospital, Clermont-Ferrand58 enrolled1 locationNCT07330856
Recruiting
Not Applicable

Efficacy of Behavioral Therapy for Chronic Refractory Cough

chronic cough
Assiut University30 enrolled1 locationNCT07488598
Recruiting

Swiss Paediatric Airway Cohort

AsthmaWheezingCough+3 more
University of Bern6,000 enrolled12 locationsNCT03505216
Recruiting
Not Applicable

Mindfulness-Oriented Respiratory Distress Symptom Intervention for Lung Cancer

Symptom ClusterBreathlessnessCoughing+3 more
The Hong Kong Polytechnic University64 enrolled1 locationNCT07281300
Recruiting
Phase 4

Sore Throat After Open Neck Elective Surgery

Postoperative Sore Throat, Cough, HoarsenessThyroid and Parathyroid Surgery
Saint Petersburg State University, Russia764 enrolled1 locationNCT07124650
Recruiting
Not Applicable

Validation of the C-mo System - Cough Monitoring

AsthmaChronic Obstructive Pulmonary DiseaseIdiopathic Pulmonary Fibrosis+5 more
Cough Monitoring Medical Solutions300 enrolled8 locationsNCT05989698
Recruiting
Phase 2

Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough

Refractory or Unexplained Chronic Cough
Nocion Therapeutics455 enrolled107 locationsNCT06504446
Recruiting
Not Applicable

Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume

Pain, AcuteCoughLung Volume+2 more
Özgül Aydemir80 enrolled1 locationNCT07411417
Recruiting
Phase 3

Efficacy and Safety of Rengalin in the Treatment of ARVI Cough in Children

Cough
Materia Medica Holding264 enrolled30 locationsNCT07171099
Recruiting

Laryngeal Cryotherapy for Refractory Neurogenic Cough

Upper-Airway Cough Syndrome
University of Texas Southwestern Medical Center28 enrolled1 locationNCT05665244
Recruiting
Phase 2

Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough

Refractory Chronic Cough
Mayo Clinic50 enrolled1 locationNCT05110144
Recruiting
Not Applicable

Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia

HypoxiaSore-throatAirway Obstruction, Postoperative+1 more
Mahidol University408 enrolled1 locationNCT07287293
Recruiting

Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough

AsthmaChronic Obstructive Pulmonary Disease (COPD)Chronic Cough (CC)
McMaster University240 enrolled6 locationsNCT06858748
Recruiting
Phase 1

Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis

Pertussis/Whooping Cough
Dalhousie University60 enrolled1 locationNCT06827470
Recruiting
Phase 3

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Refractory Chronic CoughCough
Bellus Health Inc. - a GSK company975 enrolled242 locationsNCT05600777