Phase 3 Crohn's Disease Clinical Trials
19 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–19 of 19 trials
Recruiting
Phase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Crohn's Disease
Sanofi671 enrolled12 locationsNCT07184944
Recruiting
Phase 3
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Crohn's DiseaseUlcerative Colitis
Takeda240 enrolled98 locationsNCT05442567
Recruiting
Phase 3
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Crohn's Disease
Sanofi980 enrolled196 locationsNCT07184931
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Crohn's Disease
Merck Sharp & Dohme LLC1,200 enrolled499 locationsNCT06430801
Recruiting
Phase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Crohn's DiseaseObesity or Overweight
Eli Lilly and Company290 enrolled187 locationsNCT06937099
Recruiting
Phase 3
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Inflammatory Bowel DiseasesCrohn's DiseaseUlcerative Colitis+1 more
Eli Lilly and Company150 enrolled66 locationsNCT04844606
Recruiting
Phase 3
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Crohn's Disease
AbbVie110 enrolled83 locationsNCT06332534
Recruiting
Phase 3
Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients
Crohn's Disease
Janssen-Cilag Ltd.112 enrolled84 locationsNCT06408935
Recruiting
Phase 3
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Crohn's Disease
Janssen Research & Development, LLC120 enrolled84 locationsNCT05923073
Recruiting
Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Crohn's Disease
Eli Lilly and Company90 enrolled81 locationsNCT05509777
Recruiting
Phase 3
Use of Crohn's Disease Exclusion Diet on Top of Standard Therapy Versus Standard Therapy Alone in Unstable Pediatric Crohn's Disease Patients.
Crohn's Disease
Assistance Publique - Hôpitaux de Paris120 enrolled4 locationsNCT04777656
Recruiting
Phase 3
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
Crohn's Disease
AbbVie110 enrolled85 locationsNCT05995353
Recruiting
Phase 3
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled1 locationNCT06405087
Recruiting
Phase 3
A Study of Vedolizumab in Adult Participants With Moderate to Severe Crohn's Disease
Crohn's Disease
Takeda408 enrolled41 locationsNCT05837897
Recruiting
Phase 3
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
Crohn's Disease (CD)
Takeda120 enrolled96 locationsNCT04779320
Recruiting
Phase 3
Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease
Inflammatory Bowel DiseasesCrohn's Disease
Weill Medical College of Cornell University120 enrolled1 locationNCT06274554
Recruiting
Phase 3
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled57 locationsNCT06100289
Recruiting
Phase 3
A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
Crohn's Disease
Takeda396 enrolled138 locationsNCT06227910
Recruiting
Phase 3
Phase 3 Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease
Crohn's Disease
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.228 enrolled1 locationNCT06925594