Phase 2 Crohn's Disease Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 1Phase 2

An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Crohn's Disease
National Institute of Allergy and Infectious Diseases (NIAID)35 enrolled1 locationNCT03167437
Recruiting
Phase 2

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.

Crohn's Disease
Sanofi260 enrolled138 locationsNCT06637631
Recruiting
Phase 2

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Inflammatory Bowel DiseasesCrohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)385 enrolled215 locationsNCT06226883
Recruiting
Phase 2

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease
Takeda268 enrolled194 locationsNCT06233461
Recruiting
Phase 2

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

Crohn's Disease
AbbVie540 enrolled254 locationsNCT06548542
Recruiting
Phase 2

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

Crohn's Disease
Sanofi99 enrolled66 locationsNCT06958536
Recruiting
Phase 2

Study Evaluating AZD7798 for Treatment in Crohn's Disease Patients With an Ileostomy

Crohn's Disease
AstraZeneca30 enrolled22 locationsNCT06681324
Recruiting
Phase 2

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

Crohn's DiseaseUlcerative Colitis (UC)Inflammatory Bowel Disease (IBD)
Mirador Therapeutics, Inc.140 enrolled66 locationsNCT07113522
Recruiting
Phase 2

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

Perianal Fistula Due to Crohn's Disease
Direct Biologics, LLC36 enrolled3 locationsNCT06918808
Recruiting
Phase 2

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

Crohn's DiseaseUlcerative Colitis
Takeda183 enrolled16 locationsNCT06764615
Recruiting
Phase 1Phase 2

Autologous Stem Cell Transplantation for Crohn's Disease

Crohn's Disease
Paul Szabolcs20 enrolled2 locationsNCT00692939
Recruiting
Phase 2

Clinical Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Crohn's Disease

Crohn's Disease (CD)
Biocad204 enrolled20 locationsNCT07078994
Recruiting
Phase 2

Pre-treatment With Azithromycin to Reduce Immunogenicity to to Anti-TNF Agents in Patients With Crohn's Disease

Crohn's Disease RelapseBiological Substance; Adverse Effect
Rambam Health Care Campus180 enrolled9 locationsNCT05599347
Recruiting
Phase 1Phase 2

Beta-Hydroxybutyrate Feasibility Treating IBD

Inflammatory Bowel DiseasesCrohn's Disease
University of Texas at Austin20 enrolled1 locationNCT06351124
Not Yet Recruiting
Phase 2

Asphelia Trichuris Suis Ova in Moderately Active Crohn's Disease

Crohn's Disease
Asphelia Pharmaceuticals Inc.60 enrolled1 locationACTRN12608000241336
Completed
Phase 2

Phase IIa examination of the effect of oral dosing of NV-52 on surrogate markers of inflammatory bowel disease (IBD) in patients with stable disease but with a consistent abnormality in one or more surrogate marker.

Crohn's disease and Ulcerative Colitis
Novogen Research Pty Ltd10 enrolled1 locationACTRN12607000617460