Early Phase 1 CT Clinical Trials

147 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 120 of 147 trials

Recruiting
Early Phase 1

Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia

Third Molars Extraction
Henrique Tedesco15 enrolled1 locationNCT07108465
Recruiting
Early Phase 1

Cannabis Use, Cognition, and the Endocannabinoid System in HIV

HIV-1-infection
University of California, San Diego138 enrolled1 locationNCT04883255
Recruiting
Early Phase 1

Concomitant Renal and Urinary Bladder Allograft Transplantation

Chronic Kidney DiseasesBladder DysfunctionNeurogenic Bladder+6 more
Mayo Clinic30 enrolled2 locationsNCT04626167
Recruiting
Early Phase 1

Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP

Sexually Transmitted Diseases, Bacterial
University of California, San Francisco48 enrolled1 locationNCT06414408
Recruiting
Early Phase 1

Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

Arterial HypertensionMicrovascular FunctionResistant Hypertension+1 more
National Institute of Cardiology, Laranjeiras, Brazil50 enrolled1 locationNCT06169241
Recruiting
Early Phase 1

SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

Heart Failure With Preserved Ejection FractionType2 Diabetes
The University of Texas Health Science Center at San Antonio30 enrolled1 locationNCT05057806
Recruiting
Early Phase 1

A Study of IMV102 in Patients With Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma
Suzhou Immunofoco Biotechnology Co., Ltd30 enrolled4 locationsNCT07493135
Recruiting
Early Phase 1

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1

Treatment of Chronic Obstructive Pulmonary Disease (COPD) by REGEND007 Cell Therapy

Chronic Obstructive Pulmonary Disease (COPD)
Regend Therapeutics12 enrolled1 locationNCT07355868
Recruiting
Early Phase 1

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases

Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1

Fecal Microbial Transplants for the Treatment of Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center10 enrolled1 locationNCT04975217
Recruiting
Early Phase 1

INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases

Colorectal Cancer Metastatic
Northwell Health10 enrolled1 locationNCT07172282
Recruiting
Early Phase 1

Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes

Interstitial Lung DiseaseSurfactant Dysfunction
Children's Hospital of Fudan University60 enrolled1 locationNCT04532346
Recruiting
Early Phase 1

Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder

Nicotine AddictionCraving
University of California, San Diego200 enrolled1 locationNCT06582888
Recruiting
Early Phase 1

Single-tracer Multiparametric PET Imaging

Cardiovascular DiseaseHealthy Subjects
University of California, Davis60 enrolled1 locationNCT06014515
Recruiting
Early Phase 1

A Clinical Study of AFN50 in the Treatment of Autoimmune Diseases

Relapsed/Refractory Autoimmune Diseases
Beijing Boren Hospital18 enrolled1 locationNCT07448298
Recruiting
Early Phase 1

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690
Recruiting
Early Phase 1

Respiratory and Real-time Dynamics in Exercise-Induced Paradoxical Vocal Fold Motion

Vocal Cord DysfunctionExercise-Induced Vocal Cord DysfunctionParadoxical Vocal Fold Motion
Indiana University120 enrolled1 locationNCT07420530
Recruiting
Early Phase 1

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis

Colorectal Cancer Metastatic
Northwell Health10 enrolled2 locationsNCT07193862
Recruiting
Early Phase 1

Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery

Pain ManagementLaparascopic Sleeve Gastrectomy
King Abdullah University Hospital50 enrolled1 locationNCT07429916