Early Phase 1 CT Clinical Trials
186 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 186 trials
Recruiting
Early Phase 1
Addictive Threshold of Nicotine
smoking addiction
Yale University45 enrolled1 locationNCT06096714
Recruiting
Early Phase 1
Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
Tooth Extraction Site HealingAlveolar Ridge Preservation
Egas Moniz - Cooperativa de Ensino Superior, CRL30 enrolled1 locationNCT07638358
Recruiting
Early Phase 1
The Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Chinese PLA General Hospital30 enrolled3 locationsNCT07645690
Recruiting
Early Phase 1
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
Tooth ExtractionTooth Extraction Site HealingAlveolar Bone Loss+1 more
Egas Moniz - Cooperativa de Ensino Superior, CRL30 enrolled1 locationNCT07638319
Recruiting
Early Phase 1
First-in-human Diagnostic Imaging Profile of the Theranostic Pair [68Ga]Ga-DOTA-STR-17126 and Low Dose [177Lu] Lu-DOTA-STR-17126 in Patients With Advanced or Metastatic Cancer
Metastatic Breast CancerCancerMetastatic Prostate Cancer+5 more
Integrated Haematology and Oncology Network20 enrolled1 locationNCT07608848
Recruiting
Early Phase 1
Effect of Rose Odor Exposure on Ictal Apnea
EpilepsySudden Unexpected Death in Epilepsy
Vanderbilt University Medical Center40 enrolled1 locationNCT07116421
Recruiting
Early Phase 1
18F-FTHA IMAGING OF THE INTESTINAL AND CENTRAL LYMPHATIC SYSTEM
Lymphatic Obstruction
University of Pennsylvania25 enrolled1 locationNCT07645573
Recruiting
Early Phase 1
CAR 70-BCMA CAR-T Cells for the Treatment of Relapsed or Refractory Plasma Cell Neoplasms
Relapsed or Refractory Plasma Cell Neoplasms
The General Hospital of Western Theater Command20 enrolled1 locationNCT07519187
Recruiting
Early Phase 1
Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction (HFpEF)
University of Florida70 enrolled1 locationNCT07634640
Recruiting
Early Phase 1
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients
Skin CancerCutaneous Squamous Cell Carcinoma (CSCC)Actinic Keratosis (AK)+1 more
Marissa Lobl20 enrolled2 locationsNCT07286318
Recruiting
Early Phase 1
Effects of a Hemp Product on the Pharmacokinetics and Pharmacodynamics of Clopidogrel
Interaction
Washington State University24 enrolled1 locationNCT06692933
Recruiting
Early Phase 1
Attentional Mechanisms in SCD
Subjective Cognitive Decline
Vanderbilt University Medical Center80 enrolled1 locationNCT06002477
Recruiting
Early Phase 1
Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints
Herbal Interaction
Washington State University16 enrolled1 locationNCT05846451
Recruiting
Early Phase 1
Contribution of UGT2B17 to the Pharmacokinetics of Diclofenac
Interaction
Washington State University30 enrolled1 locationNCT06053411
Recruiting
Early Phase 1
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
transitional cell carcinomaSoft Tissue SarcomaMelanoma+12 more
University of California, Irvine25 enrolled1 locationNCT07628634
Recruiting
Early Phase 1
A Study of Automated Axicabtagene Ciloleucel for R/R Large B-cell Lymphoma.
Relapsed/Refractory Large B-Cell Lymphoma
Shenzhen Fosun Kairos Biotechnology Co., Ltd.12 enrolled6 locationsNCT07606937
Recruiting
Early Phase 1
Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach
Interaction
Washington State University16 enrolled1 locationNCT06693960
Recruiting
Early Phase 1
Autologous BCMA-targeted CAR-T Cell Injection for Relapsed/Refractory Light Chain Amyloidosis
AL AmyloidosisSystemic Light Chain AmyloidosisRelapsed/Refractory Light Chain Amyloidosis
Beijing Boren Hospital30 enrolled1 locationNCT07626476
Recruiting
Early Phase 1
A Clinical Study to Evaluate the Safety and Efficacy of GT801 Injection in the Treatment of Moderate to Severe Refractory Autoimmune Diseases
Moderate to Severe Refractory Autoimmune Diseases
Vivacta Biotechnology (Shanghai) Co., Ltd.22 enrolled1 locationNCT07614191
Recruiting
Early Phase 1
Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals
Pancreatic CancerPancreatic Ductal AdenocarcinomaPDAC+2 more
Dana-Farber Cancer Institute5,000 enrolled2 locationsNCT06122896