Phase 2 CTS Clinical Trials

36 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 36 trials

Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Phase 2

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

NeoplasmsVomitingNausea+1 more
Eli Lilly and Company204 enrolled67 locationsNCT07169851
Recruiting
Phase 2

A Multicenter, Randomized, Double-Masked, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of ZOC2017217 in Subjects With Age-Related Cataract

Age Related Cataracts
Ocusun Ophthalmic Pharmaceutical (Guangzhou) Co., Ltd.40 enrolled21 locationsNCT07395986
Recruiting
Phase 2

A Multicenter, Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of QY201 Tablets in Subjects With Non-Segmental Vitiligo

Adult Subjects With Non-Segmental Vitiligo
E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd.200 enrolled1 locationNCT07712523
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Phase 2

Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women

Focus is on Healthy Subjects
Lallemand Health Solutions72 enrolled1 locationNCT07246161
Recruiting
Phase 2

Timely Integration of Palliative Care in Oncology Care for Patients Referred for Palliative Radiotherapy on Bone Metastases: A Randomized Trial

RadiotherapyBone Metastases in Subjects With Advanced Cancer
Roxanne Gal246 enrolled5 locationsNCT06805396
Recruiting
Phase 2Phase 3

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 2

MAGIC Ruxolitinib for aGVHD

Acute Graft Versus Host Diseaseadverse effectsAllogeneic Bone Marrow Transplantation
John Levine98 enrolled14 locationsNCT06936566
Recruiting
Phase 1Phase 2

Immune Tolerance Induction After Liver Transplantation

Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting
Phase 2

A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1

Healthy Subjects
Cerus Corporation70 enrolled2 locationsNCT07015437
Recruiting
Phase 2

Human Craniomaxillofacial Allotransplantation

Facial InjuriesTraumatic Wounds and InjuriesCraniofacial Injuries+3 more
Johns Hopkins University15 enrolled1 locationNCT01889381
Recruiting
Phase 2

Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Locally Advanced Cervical CancerFemale, Age ≥ 18 Years OldNo Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy+6 more
The First Affiliated Hospital of Zhengzhou University29 enrolled1 locationNCT07104149
Recruiting
Phase 1Phase 2

Retina is a Marker for Cerebrovascular Heath

Cerebral Small Vessel DiseasesCerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and LeukoencephalopathyCerebral Microbleeding+1 more
Mayo Clinic100 enrolled1 locationNCT04753970
Recruiting
Phase 2

Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

Cardiovascular DiseasesHeart DiseasesCardiovascular Abnormalities+8 more
Nationwide Children's Hospital24 enrolled1 locationNCT04467671
Recruiting
Phase 2

Study of MT1013 Injection for the Treatment of Secondary Hyperparathyroidism (SHPT) Patients With Chronic Kidney Disease Undergoing Maintenance Dialysis

Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis
Shaanxi Micot Pharmaceutical Technology Co., Ltd.310 enrolled1 locationNCT06976177
Recruiting
Phase 2

A Study to Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease.

Chronic Kidney Disease Stage 3Chronic Renal FailureMechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte Homeostatis+1 more
Klinikum Nürnberg100 enrolled2 locationsNCT05884866
Recruiting
Phase 2

Investigating the effect of medicinal cannabis on the symptoms and side effects of chemotherapy in people with cancer.

chemotherapy treatment side effects
Central Adelaide Local Health Network (CALHN)176 enrolled3 locationsACTRN12622000419763
Not Yet Recruiting
Phase 2

A Phase 2 Study to Evaluate the Efficacy, Safety and Tolerability of CBL 514 Injection on Thigh Subcutaneous Fat

Healthy to overweight subjects with undesirable subcutaneous fat thickness in thighs
Caliway Biopharmaceuticals Australia Pty Ltd18 enrolled1 locationACTRN12620001153909
Recruiting
Phase 2

A Phase 2a Study to Evaluate the Preliminary Efficacy and Safety of CBL-514 Injection on Convexity or Fullness of Abdominal Subcutaneous Fat in Healthy Volunteers

Healthy subjects with undesirable subcutaneous fat thickness in belly
Caliway Biopharmaceuticals Australia Pty Ltd66 enrolled1 locationACTRN12619001580167